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[裂谷热,一个兽医和医学问题(作者译)]

[Rift Valley Fever, a Veterinary and Medical Problem (author's transl)].

作者信息

van Tongeren H A

出版信息

Tijdschr Diergeneeskd. 1979 Sep 1;104(17):659-73.

PMID:494210
Abstract

Rift Valley fever probably occurred in East and South Africa for many years, where it occasionally caused sever epizootics among sheep and to a less extent in cattle and goats. Particularly newborn animals fall victims to the disease, whereas the majority of pregnant ewes and cows abort. In recent years, the disease spread to the Sudan and reached the Nile delta in 1977, where it not only caused an epizootic but also an epidemic among the population, resulting in approximately 18,000 cases and nearly 600 deaths. During the summer of 1978, the disease was observed again so that the virus must have overwintered in the newly infested area. The disease in animals and subsequently in man, displaying four different clinical forms, is discussed. The limited knowledge of the pathogenesis and epidemiology is stressed particular attention being paid to the Egyptian epizootic and epidemic. Because of inadequate knowledge of the clinical features, pathogenesis and other data, the disease among cattle was not detected until from five to six months after it had broken out. The spread of Rift Valley fever to the north-eastern part of Africa forms a potential threat of dissemination of the virus to neighbouring countries, situated on the two adjacent continents of Asia and Europe, and it is a real one. International travel and movement of goods and animals as well as the political situation in that area involves the danger of the Rift Valley fever virus also being transferred to new areas and becoming established there.

摘要

裂谷热可能在东非和南非存在多年,偶尔会在绵羊中引发严重的动物流行病,在牛和山羊中引发的程度相对较轻。尤其是新生动物易患此病,而大多数怀孕的母羊和母牛会流产。近年来,该病蔓延至苏丹,并于1977年到达尼罗河三角洲,在那里它不仅引发了动物流行病,还在人群中引发了疫情,导致约18000例病例和近600人死亡。1978年夏天,该病再次出现,因此病毒肯定在新感染地区越冬了。本文讨论了动物及随后人类中的这种疾病所呈现的四种不同临床形式。强调了对发病机制和流行病学的了解有限,尤其关注埃及的动物流行病和疫情。由于对临床特征、发病机制及其他数据了解不足,牛群中的疾病直到爆发五到六个月后才被发现。裂谷热向非洲东北部的蔓延对病毒传播到位于亚洲和欧洲这两个相邻大陆的邻国构成了潜在威胁,而且这是一个现实的威胁。国际旅行、货物和动物的流动以及该地区的政治局势都存在裂谷热病毒也被转移到新地区并在那里传播开来的危险。

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