von Gossler W, Walpoth B, Geroulanos S, Hess O M, Turina M
Thorac Cardiovasc Surg. 1979 Aug;27(4):256-9. doi: 10.1055/s-0028-1096256.
Two experimental models were studied to determine the hemodynamic consequences of atrial volume reduction as observed after operative correction of transposition of the great arteries. The volume of the left atrium (LA) was reduced either by inflation of an intracavitary balloon (group A) or by surgical intervention (group B) to 50--60% of the control values as determined by angiography. The angiographic data correlated well with the true volumes obtained by water displacement. This major reduction of LA volume caused small but constant hemodynamic changes. Although the LA stroke volume decreased by 50% and the LA/LV volume relation was reduced by 50% (from 0.42 to 0.21), there was only a slight increase of pulmonary artery pressure (7% in group A and 14% in group B) and a slight decrease in cardiac index (13% in group A and 10% in group B) and in left ventricular end-diastolic pressure (9% in group A and 11% in group B). The reduction of atrial volume results in only minor functional alteration of the intact heart.
研究了两种实验模型，以确定在大动脉转位手术矫正后观察到的心房容积减少的血流动力学后果。通过腔内球囊扩张（A组）或手术干预（B组）将左心房（LA）容积减少至血管造影确定的对照值的50%-60%。血管造影数据与通过水置换获得的真实容积密切相关。LA容积的这种大幅减少引起了小而持续的血流动力学变化。尽管LA每搏输出量减少了50%，LA/LV容积比降低了50%（从0.42降至0.21），但肺动脉压仅略有升高（A组为7%，B组为14%），心脏指数略有下降（A组为13%，B组为10%），左心室舒张末期压力也略有下降（A组为9%，B组为11%）。心房容积的减少仅导致完整心脏的轻微功能改变。
