氯法齐明治疗未经治疗的瘤型麻风的对照临床试验。
Controlled clinical trial of clofazimine in untreated lepromatous leprosy.
作者信息
Karat A B, Jeevaratnam A, Karat S, Rao P S
出版信息
Br Med J. 1971 Nov 27;4(5786):514-6. doi: 10.1136/bmj.4.5786.514.
Abstract
A comparison of clofazimine and dapsone in the management of untreated lepromatous leprosy showed no significant differences between the two drugs in terms of morphological and bacterial indices. The incidence of erythema nodosum leprosum was similar in the two groups. Since dapsone is cheaper than clofazimine it remains the drug of choice for the routine management of untreated lepromatous leprosy.
摘要
氯法齐明与氨苯砜治疗未经治疗的瘤型麻风的比较显示，两种药物在形态学和细菌学指标方面无显著差异。两组中麻风结节性红斑的发生率相似。由于氨苯砜比氯法齐明便宜，它仍然是未经治疗的瘤型麻风常规治疗的首选药物。
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