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[低浓度镧处理的L细胞培养物中特化细胞间连接的超微结构]

[Ultrastructure of the specialized intercellular contacts in an L-cell culture treated with low concentrations of lanthanum].

作者信息

Snigirevskaia E S, Potapova T V, Komissarchik Ia Iu, Chailakhian L M

出版信息

Tsitologiia. 1979 Aug;21(8):882-6.

PMID:494391
Abstract

The electron microscope study of L-cells treated with 1 mM lanthanum has shown an increased amount of gap-like junctions and a decreased number of tight junctions compared to the norm. No damage in the plasma membrane structure and other cell organoids was observed. This may suggest that following the above treatment, the amplified intercellular exchange is associated with the increase in the quantity of intercellular highly permeable junctions. In this case lanthanum may serve as a membrane structure modificator. This effect must be taken into account when the electron microscopists use the lanthanum label for studying specialized intercellular junctions.

摘要

对用1 mM镧处理的L细胞进行的电子显微镜研究表明,与正常情况相比,间隙样连接的数量增加,紧密连接的数量减少。未观察到质膜结构和其他细胞器有损伤。这可能表明,经过上述处理后,细胞间交换的增强与细胞间高渗透性连接数量的增加有关。在这种情况下,镧可能作为一种膜结构修饰剂。当电子显微镜工作者使用镧标记来研究特殊的细胞间连接时,必须考虑到这种效应。

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