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Intramuscular and intravenous administration of small doses of 2-pyridinium aldoxime methochloride to man.

作者信息

Sidell F R, Groff W A

出版信息

J Pharm Sci. 1971 Aug;60(8):1224-8. doi: 10.1002/jps.2600600823.

DOI:10.1002/jps.2600600823
PMID:4945277
Abstract
摘要

相似文献

1
Intramuscular and intravenous administration of small doses of 2-pyridinium aldoxime methochloride to man.向人体肌肉注射和静脉注射小剂量的氯解磷定。
J Pharm Sci. 1971 Aug;60(8):1224-8. doi: 10.1002/jps.2600600823.
2
Toxogonin: oral administration to man.毒扁豆碱：对人体的口服给药。
J Pharm Sci. 1971 Jun;60(6):860-3. doi: 10.1002/jps.2600600611.
3
Human toxicity of various oximes. 2-Pyridine aldoxime methyl chloride, its methane sulfonate salt, and 1,1'-trimethylenebis-(4-formylpyridinium chloride).
Arch Environ Health. 1967 Nov;15(5):599-608. doi: 10.1080/00039896.1967.10664975.
4
Blood concentrations of N,N'-trimethylenebis(pyridinium-4-aldoxime) (TMB-4) and N,N'-oxydimethlenebis (pyridinium-4-aldoxime) (toxogonin) after intravenous and intramuscular administration in the dog.犬静脉注射和肌肉注射N,N'-三亚甲基双(吡啶-4-醛肟)(TMB-4)和N,N'-氧代二亚甲基双(吡啶-4-醛肟)(双复磷)后的血药浓度
Biochem Pharmacol. 1967 Dec;16(12):2435-8. doi: 10.1016/0006-2952(67)90230-4.
5
Toxogonin: blood levels and side effects after intramuscular administration in man.毒扁豆碱：人体肌肉注射后的血药浓度及副作用
J Pharm Sci. 1970 Jun;59(6):793-7. doi: 10.1002/jps.2600590615.
6
Modification of the effects of atropine on human heart rate by pralidoxime.
Clin Pharmacol Ther. 1970 Jan-Feb;11(1):68-76. doi: 10.1002/cpt197011168.
7
Pralidoxime mesylate absorption and heart rate response to atropine sulphate following intramuscular administration of solution mixtures.肌肉注射溶液混合物后，甲磺磷解磷定的吸收及对硫酸阿托品的心率反应。
Br J Clin Pharmacol. 1975 Aug;2(4):333-8. doi: 10.1111/j.1365-2125.1975.tb02780.x.
8
Toxogonin and pralidoxime: kinetic comparison after intravenous administration to man.氯磷定和碘解磷定：静脉注射给人后的动力学比较。
J Pharm Sci. 1972 Nov;61(11):1765-9. doi: 10.1002/jps.2600611115.
9
Disposition kinetics of 2-pyridine aldoxime methochloride in Bubalus bubalis.2-吡啶醛肟甲基氯化物在水牛体内的处置动力学
J Vet Pharmacol Ther. 1989 Mar;12(1):103-8. doi: 10.1111/j.1365-2885.1989.tb00648.x.
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Effects of 2-pyridinium aldoxine methochloride and atropine in relation to elevation of blood pH in soman-poisoned dogs.氯化2-吡啶醛肟和阿托品对梭曼中毒犬血液pH值升高的影响。
Biochem Pharmacol. 1969 Feb;18(2):419-27. doi: 10.1016/0006-2952(69)90219-6.

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Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor.
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4
Intramuscular kinetics and dosage regimens for pralidoxime in buffalo calves (Bubalus bubalis).
Vet Res Commun. 2001 May;25(4):301-9. doi: 10.1023/a:1010630709407.
5
Blood concentrations of 2,3-butanedione monoxime and some blood biochemical changes in Bubalus bubalis after intramuscular administration of this cholinesterase reactivator.肌肉注射这种胆碱酯酶复活剂后水牛体内2,3 - 丁二酮单肟的血药浓度及一些血液生化变化。
Vet Res Commun. 1987;11(3):275-80. doi: 10.1007/BF00570925.
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A review of organophosphate poisoning.有机磷中毒综述。
Med Toxicol Adverse Drug Exp. 1988 Sep-Oct;3(5):350-75. doi: 10.1007/BF03259890.
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Pharmacokinetics of pralidoxime chloride. A comparative study in healthy volunteers and in organophosphorus poisoning.氯解磷定的药代动力学。在健康志愿者和有机磷中毒患者中的对比研究。
Arch Toxicol. 1989;63(5):416-8. doi: 10.1007/BF00303133.
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Plasma concentrations of pralidoxime methylsulphate in organophosphorus poisoned patients.
Arch Toxicol. 1992;66(4):260-6. doi: 10.1007/BF02307171.
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Protection against the effects of anticholinesterases on the latencies of action potentials in mouse skeletal muscles.预防抗胆碱酯酶对小鼠骨骼肌动作电位潜伏期的影响。
Br J Pharmacol. 1992 Nov;107(3):867-72. doi: 10.1111/j.1476-5381.1992.tb14539.x.
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Critical compilation of terminal half-lives, percent excreted unchanged, and changes of half-life in renal and hepatic dysfunction for studies in humans with references.对人类研究中终末半衰期、原形药物排泄百分比以及肾功能和肝功能不全时半衰期变化进行批判性汇编，并列出参考文献。
J Pharmacokinet Biopharm. 1975 Oct;3(5):333-83. doi: 10.1007/BF01082306.