[Carbohydrate metabolism investigations in children of diabetic mothers (author's transl)].

A follow-up examination was conducted in 65 children aged up to 7 years whose mothers manifested diabetes mellitus during pregnancy and who had to be transferred to the Children's Hospital at Glanzing, Vienna for post partum complications. No case of manifest diabetes mellitus was recorded. Carbohydrate metabolism was investigated by determining immunological insulin (IRI) and the insulinogenic index during an oral glucose tolerance (OGTT). Three children showed pathological findings; two of them showed incomplete or delayed insulin secretion during the OGTT. One child displayed an inadequate rise in the insulinogenic index with high individual insulin values during the OGTT, which gave border line results. We support the point of view that children of diabetic mothers should be controlled with regard to carbohydrate metabolism regularly to recognize premanifest diabetic states at an early stage.