Fick R B, Isturiz R, Cadman E C
Yale J Biol Med. 1979 Jul-Aug;52(4):339-44.
We report a case of septic arthritis caused by the fastidious gram-negative rod Campylobacter fetus. We suggest that the organism may be part of the endogenous flora and that the clinical infections tend to occur in compromised hosts. Our patient is the first to be described with multiple myeloma and C. fetus septic arthritis. The documented cases of culture-proven C. fetus septic arthritis reported to date have occurred in three men and one woman, all in the seventh and eighth decades of life, with a mono-articular large joint distribution. The septic arthritis always occurred in previously injured joints and curiously enough need not be associated with a toxic-appearing patient. C. fetus infections are also associated with the signs and symptoms of clinical thrombophlebitis. We stress caution in establishing this diagnosis of phlebitis on clinical evaluation only and urge differentiation of true deep vein thrombophlebitis from pseudothrombophlebitis or dissected popliteal synovial cyst. This latter diagnosis may be made non-invasively by ultrasound techniques.
我们报告一例由苛养革兰氏阴性杆菌胎儿弯曲菌引起的化脓性关节炎病例。我们认为该病原体可能是内源性菌群的一部分,且临床感染往往发生在免疫功能低下的宿主中。我们的患者是首例被描述为患有多发性骨髓瘤和胎儿弯曲菌化脓性关节炎的病例。迄今为止报道的经培养证实的胎儿弯曲菌化脓性关节炎病例有3名男性和1名女性,均为70和80多岁,关节分布为单关节大关节。化脓性关节炎总是发生在先前受伤的关节,而且奇怪的是不一定与有中毒表现的患者相关。胎儿弯曲菌感染还与临床血栓性静脉炎的体征和症状有关。我们强调仅通过临床评估来确诊静脉炎时要谨慎,并敦促区分真正的深静脉血栓性静脉炎与假性血栓性静脉炎或腘窝滑膜囊肿破裂。后一种诊断可以通过超声技术进行无创诊断。