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本文引用的文献

1
The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera.蛋白质在经单宁酸处理的红细胞上的吸附以及随后抗蛋白质血清引起的血细胞凝集。
J Exp Med. 1951 Feb;93(2):107-20. doi: 10.1084/jem.93.2.107.
2
STUDIES ON THE ADJUVANT ACTION OF BACTERIAL ENDOTOXINS ON ANTIBODY FORMATION. VI. ENHANCEMENT OF ANTIBODY FORMATION BY NUCLEIC ACIDS.细菌内毒素对抗体形成的佐剂作用研究。VI. 核酸对抗体形成的增强作用。
J Immunol. 1965 Mar;94:416-22.
3
Antibody formation. IV. Formation of rapidly and slowly sedimenting antibodies and immunological memory to bacteriophage phi-X 174.抗体形成。IV. 针对噬菌体φ-X 174的快速和慢速沉降抗体的形成及免疫记忆
J Exp Med. 1963 Mar 1;117(3):457-77. doi: 10.1084/jem.117.3.457.
4
Generalized Shwartzman reaction in the pregnant golden hamster.
Science. 1963 Mar 8;139(3558):923-4. doi: 10.1126/science.139.3558.923.
5
Effect of colchicine on antibody response in hamsters.秋水仙碱对仓鼠抗体反应的影响。
Proc Soc Exp Biol Med. 1962 Mar;109:628-30. doi: 10.3181/00379727-109-27290.
6
Failure of bacterial endotoxin to produce the generalized Shwartzman reaction in the Syrian hamster.细菌内毒素在叙利亚仓鼠中未能引发全身性施瓦茨曼反应。
J Bacteriol. 1967 Sep;94(3):590-6. doi: 10.1128/jb.94.3.590-596.1967.
7
The effects of endotoxin on the immune response in the rat. II. Antibodies formed against bovine gamma-globulin in the splenectomized rat.内毒素对大鼠免疫反应的影响。II. 脾切除大鼠体内针对牛γ球蛋白形成的抗体。
Lab Invest. 1967 May;16(5):782-94.
8
The effects of endotoxin on the immune response in the rat. I. Antibodies formed against bovine gamma-globulin in the intact rat.内毒素对大鼠免疫反应的影响。I. 正常大鼠体内针对牛γ球蛋白形成的抗体。
Lab Invest. 1967 May;16(5):768-81.
9
Role of antibodies in reactions to gram-negative bacterial endotoxins.抗体在革兰氏阴性菌内毒素反应中的作用。
Ann N Y Acad Sci. 1966 Jun 30;133(2):727-45. doi: 10.1111/j.1749-6632.1966.tb52402.x.

细菌内毒素和秋水仙碱对仓鼠抗体形成的佐剂作用。

Adjuvant action of bacterial endotoxin and colchicine on antibody formation in the hamster.

作者信息

Merritt K

出版信息

Infect Immun. 1971 Oct;4(4):393-6. doi: 10.1128/iai.4.4.393-396.1971.

DOI:10.1128/iai.4.4.393-396.1971
PMID:4949499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC416319/
Abstract

Endotoxin was demonstrated not to act as an adjuvant in the primary antibody response in the Syrian hamster. Minimal adjuvant action was demonstrable in antibody formation to a second injection of bovine gamma globulin. The immunological status of the hamster towards the endotoxin did not alter this weak adjuvant action. It was confirmed that the antimitotic drug colchicine will act as an adjuvant in the primary antibody response to sheep red blood cells but not to bovine gamma globulin or endotoxin in the Syrian hamster.

摘要

内毒素在叙利亚仓鼠的初次抗体反应中未表现出佐剂作用。在对第二次注射牛γ球蛋白的抗体形成中，可证明其佐剂作用极小。仓鼠对内毒素的免疫状态并未改变这种微弱的佐剂作用。已证实抗有丝分裂药物秋水仙碱在叙利亚仓鼠对绵羊红细胞的初次抗体反应中可作为佐剂，但对牛γ球蛋白或内毒素则不然。