Anniko M
Acta Otolaryngol. 1979;88(3-4):211-9. doi: 10.3109/00016487909137162.
Postnatal (newborn and mature) inner ear organs from CBA/CBA mouse and guinea pig were analysed concerning hair cell survival in an in vitro system. After only a few days in the artificial surroundings a transformation of hair cell characteristics occurred, in the form of either loss of sensory hairs (cochlear hair cells) or hair fusion (vestibular hair cells), although the hair cell itselt survived for a considerably longer time. Intracellular myelin figures became evident after 2--3 days in culture. However, a considerable individual variation among hair cells was observed concerning the ultrastructure of the cell at this stag in vitro. Completely normal hair cells could in rare cases be recognised after 1 week in organ culture (cochlear inner hair cells of the CBA/CBA mouse). Loss of the surface structures of the hair cells is likely to constitute an irreversible transformation not in agreement with the true hair cell characteristics.
对来自CBA/CBA小鼠和豚鼠的产后（新生和成熟）内耳器官在体外系统中进行毛细胞存活情况分析。在人工环境中仅培养几天后，毛细胞特征就发生了转变，表现为感觉毛缺失（耳蜗毛细胞）或毛发融合（前庭毛细胞），尽管毛细胞本身存活了相当长的时间。培养2至3天后，细胞内髓鞘样结构变得明显。然而，在此体外阶段，观察到毛细胞在细胞超微结构方面存在相当大的个体差异。在器官培养1周后，极少数情况下可识别出完全正常的毛细胞（CBA/CBA小鼠的耳蜗内毛细胞）。毛细胞表面结构的丧失可能构成与真正毛细胞特征不符的不可逆转变。
