Anniko M, Wersäll J
Arch Otorhinolaryngol. 1979;224(1-2):25-30. doi: 10.1007/BF00455220.
The embryologic labyrinthine development of the CBA/CBA mouse occurs parallell in vivo and in vitro. Regarding post partum inner ears, either as cultured otocysts passing a corresponding time in vitro or inner ear explants of newborn/mature animals, the extracorporal system becomes unable to maintain specialized hair cell structures for more than a few days. The sensory cells themselves, however, survive for considerably longer time. Vestibular hair cells show sensory hair fusion. Cochlear hair cells loose their surface structures but the sensory hair rootlets penetrating into the cuticle are preserved. Post partum inner ears from the guinea pig reacted in a similar way in vitro as did labyrinths from the CBA/CBA mouse.
CBA/CBA小鼠的胚胎期迷路发育在体内和体外是平行发生的。对于产后内耳，无论是在体外经过相应时间培养的耳囊，还是新生/成年动物的内耳外植体，体外系统都无法在数天以上维持特殊的毛细胞结构。然而，感觉细胞本身存活的时间要长得多。前庭毛细胞出现感觉毛融合。耳蜗毛细胞失去其表面结构，但穿透角质层的感觉毛小根得以保留。豚鼠产后内耳在体外的反应与CBA/CBA小鼠的迷路相似。
