Tanos B
Acta Physiol Acad Sci Hung. 1979;53(1):1-7.
Experiments were performed in anaesthetized and splenectomized dogs to influence the intravascular distribution of erythrocytes and plasma within the vascular bed. Blood volume was determined by double-isotope labelling of red cells and plasma. A significant decrease of F cells-value was found after posthaemorrhagic haemodilution and after haemodilution induced by homologous plasma. The administration of epsilon-amino caproic acid and bovine thrombin was followed by a significant increase of F cells-value. An interdependence of coagulability and F cells-value is suggested. The increase of haematocrit was followed by an increase of TPR, which, however, was only half of the value that would have been anticipated on the basis of the increase of viscosity when measured in normal-bore viscometers. This points to the possibility that blood flowing in the resistance vessels undergoes a certain spontaneous separation of cells and plasma and its haematocrit will be lower than in the large vessels. Cell separation in different organs having different haematocrit values and blood volumes probably affects total body haematocrit and F cells-value.
在麻醉和脾切除的狗身上进行了实验，以影响血管床内红细胞和血浆的血管内分布。通过对红细胞和血浆进行双同位素标记来测定血容量。出血后血液稀释以及同源血浆诱导的血液稀释后，F细胞值显著降低。给予ε-氨基己酸和牛凝血酶后，F细胞值显著增加。提示了凝血性与F细胞值之间的相互依赖性。血细胞比容升高后，总外周阻力（TPR）增加，然而，这只是在正常管径粘度计中根据粘度增加所预期值的一半。这表明在阻力血管中流动的血液可能会发生一定程度的细胞与血浆自发分离，其血细胞比容将低于大血管中的血细胞比容。不同器官中具有不同血细胞比容值和血容量的细胞分离可能会影响全身血细胞比容和F细胞值。
