大鼠肾脏与尿液激肽释放酶之间的化学关系
Chemical relations between renal and urinary kallikrein of rat.
作者信息
Porcelli G, Marini-Bettòlo G B, Croxatto H R, Di Jorio M
出版信息
Adv Exp Med Biol. 1979;120A:221-4. doi: 10.1007/978-1-4757-0926-1_22.
PMID:495311
Abstract
The ratio in micron-Moles between each aminoacid residue of both hydrolized renal and urinary kallikrein of rat, is about 1.00 +/- 0.3. Except for Glu, His and Glucosamine a good proportion between all residues of both enzymes was obtained. It is probable that the different molecular weight, respectively 40,000 for the renal kallikrein and 32,000 for the urinary enzyme, is an artefact of the different procedures used for the purification of rat kallikrein.
摘要
大鼠水解肾激肽释放酶和尿激肽释放酶中各氨基酸残基的微摩尔比约为1.00±0.3。除了谷氨酸、组氨酸和氨基葡萄糖外，两种酶的所有残基之间都有较好的比例。肾脏激肽释放酶分子量为40,000，尿激肽释放酶分子量为32,000，这种分子量差异可能是大鼠激肽释放酶纯化过程中使用的不同方法导致的假象。
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