Greenberg B, Chatterjee K, Parmley W W, Werner J A, Holly A N
Am Heart J. 1979 Dec;98(6):742-51. doi: 10.1016/0002-8703(79)90473-3.
The influence of left ventricular filling pressure on the atrial contribution filling pressure and atrial contribution was seen in studies done at baseline (PCW (r=-.53, p less than .025), as well as in studies done after PCW was modified by volume expansion and/or nitrates (r=-.53, p less than .005). At baseline, atrial contribution averaged 9.3 +/- 1.3 c.c./M.2 in patients with PCW less than 20 mm. Hg, while it was only 2.4 +/- 1.2 c.c./M.2 in patients with PCW greater than or equal to 20 mm. Hg (p less than .005). Atrial contribution was significantly greater in patients who had no history of heart failure when they were volume loaded to a PCW above 20 mm. Hg than in patients with impaired ventricular function whose baseline PCW was above 20 mm. Hg. Thus, atrial contribution tends to be less effective in augmenting cardiac output when filling pressure is already elevated, particularly in patients with impaired left ventricular function.
左心室充盈压对心房充盈压贡献及心房贡献的影响在基线研究中可见（肺毛细血管楔压（PCW），r = -0.53，p < 0.025），在通过容量扩充和/或硝酸盐改变PCW后的研究中也可见（r = -0.53，p < 0.005）。基线时，PCW小于20 mmHg的患者心房贡献平均为9.3±1.3 cc/M²，而PCW大于或等于20 mmHg的患者心房贡献仅为2.4±1.2 cc/M²（p < 0.005）。当无心力衰竭病史的患者容量负荷至PCW高于20 mmHg时，其心房贡献显著大于基线PCW高于20 mmHg的心室功能受损患者。因此，当充盈压已经升高时，尤其是在左心室功能受损的患者中，心房贡献在增加心输出量方面往往效果较差。
