Agar-gel precipitin-inhibition technique for plague antibody determinations.

An application of the agar-gel precipitin-inhibition technique we described previously can be used to detect plague antibodies in human and animal sera after a series of plague vaccine inoculations or after exposure to Pasteurella pestis. Determination of the minimal reacting concentrations of the plague antigen and antibody reagents, methods for combining reagents, and length of incubation periods are discussed.