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J Bacteriol. 1966 Mar;91(3):930-3. doi: 10.1128/jb.91.3.930-933.1966.
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引用本文的文献

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Comparative efficacy of Bacillus anthracis live spore vaccine and protective antigen vaccine against anthrax in the guinea pig.炭疽芽孢杆菌活芽孢疫苗和保护性抗原疫苗在豚鼠体内抗炭疽的比较疗效
Infect Immun. 1986 May;52(2):509-12. doi: 10.1128/iai.52.2.509-512.1986.

本文引用的文献

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Studies on immunity in anthrax. II. In vitro elaboration of protective antigen by non-proteolytic mutants of Bacillus anthracis.炭疽免疫研究。II. 炭疽芽孢杆菌非蛋白水解突变体在体外产生保护性抗原
J Exp Med. 1951 Jun;93(6):523-7. doi: 10.1084/jem.93.6.523.
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Immunological studies of anthrox. II. Levels of immunity against Bacillus anthracis obtained with protective antigen and live vaccine.
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IMMUNOLOGIC STUDIES OF ANTHRAX. III. COMPARISON OF ANTIBODY TITER AND IMMUNITY INDEX AFTER ANTHRAX IMMUNIZATION.
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Studies on immunity in anthrax. IX. Effect of variations in cultural conditions on elaboration of protective antigen by strains of Bacillus anthracis.炭疽免疫研究。IX. 培养条件变化对炭疽芽孢杆菌菌株保护性抗原产生的影响。
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Immunological studies of anthrax. I. An index to determine quantitative immunization.炭疽的免疫学研究。I. 一种用于确定定量免疫的指标。
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Elaboration of protective antigen of Bacillus anthracis under anaerobic conditions.在厌氧条件下炭疽芽孢杆菌保护性抗原的精制
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Studies on immunity in anthrax. VI. Immunizing activity of protective antigen against various strains of Bacillus anthracis.炭疽免疫研究。VI. 保护性抗原对不同炭疽芽孢杆菌菌株的免疫活性
J Immunol. 1955 Aug;75(2):129-33.
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Studies on immunity in anthrax. III. Elaboration of protective antigen in a chemically defined, non-protein medium.炭疽免疫研究。III. 在化学成分明确的非蛋白质培养基中保护性抗原的制备。
J Immunol. 1954 Apr;72(4):263-9.
9
Studies on a protective antigen produced in vitro from Bacillus anthracis: purification and chemistry of the antigen.炭疽芽孢杆菌体外产生的一种保护性抗原的研究：抗原的纯化与化学性质
Br J Exp Pathol. 1954 Apr;35(2):153-65.
10
Studies on a protective antigen produced in vitro from Bacillus anthracis: medium and methods of production.炭疽芽孢杆菌体外产生的一种保护性抗原的研究：培养基及生产方法。
Br J Exp Pathol. 1954 Apr;35(2):144-52.

非蛋白水解性、无毒力的炭疽芽孢杆菌作为活疫苗。

Nonproteolytic, avirulent Bacillus anthracis as a live vaccine.

作者信息

Fubra E S

出版信息

J Bacteriol. 1966 Mar;91(3):930-3. doi: 10.1128/jb.91.3.930-933.1966.

DOI:10.1128/jb.91.3.930-933.1966
PMID:4956337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC315980/
Abstract

Fubra, Ernest S. (Federal Department of Veterinary Research, Vom, Nigeria). Nonproteolytic, avirulent Bacillus anthracis as a live vaccine. J. Bacteriol. 91:930-933. 1966.-A nonproteolytic mutant, derived from the Sterne strain of Bacillus anthracis by exposure to ultraviolet radiation, was used for vaccination of guinea pigs. Vaccine prepared from the parent Sterne strain was used in comparable immunization procedure. Comparison of the protection induced by the two vaccines showed that use of the nonproteolytic mutant was from 10 to 1,000 times as effective as the Sterne strain.

摘要

富布拉，欧内斯特·S.（尼日利亚翁的联邦兽医研究部）。非蛋白水解性、无毒炭疽芽孢杆菌作为活疫苗。《细菌学杂志》91:930 - 933。1966年。——通过紫外线照射从炭疽芽孢杆菌斯特恩菌株衍生出的一种非蛋白水解性突变体，用于豚鼠的疫苗接种。用亲本斯特恩菌株制备的疫苗用于类似的免疫程序。对两种疫苗诱导的保护作用进行比较表明，使用非蛋白水解性突变体的效果是斯特恩菌株的10至1000倍。