非蛋白水解性、无毒力的炭疽芽孢杆菌作为活疫苗。
Nonproteolytic, avirulent Bacillus anthracis as a live vaccine.
作者信息
Fubra E S
出版信息
J Bacteriol. 1966 Mar;91(3):930-3. doi: 10.1128/jb.91.3.930-933.1966.
Abstract
Fubra, Ernest S. (Federal Department of Veterinary Research, Vom, Nigeria). Nonproteolytic, avirulent Bacillus anthracis as a live vaccine. J. Bacteriol. 91:930-933. 1966.-A nonproteolytic mutant, derived from the Sterne strain of Bacillus anthracis by exposure to ultraviolet radiation, was used for vaccination of guinea pigs. Vaccine prepared from the parent Sterne strain was used in comparable immunization procedure. Comparison of the protection induced by the two vaccines showed that use of the nonproteolytic mutant was from 10 to 1,000 times as effective as the Sterne strain.
摘要
富布拉，欧内斯特·S.（尼日利亚翁的联邦兽医研究部）。非蛋白水解性、无毒炭疽芽孢杆菌作为活疫苗。《细菌学杂志》91:930 - 933。1966年。——通过紫外线照射从炭疽芽孢杆菌斯特恩菌株衍生出的一种非蛋白水解性突变体，用于豚鼠的疫苗接种。用亲本斯特恩菌株制备的疫苗用于类似的免疫程序。对两种疫苗诱导的保护作用进行比较表明，使用非蛋白水解性突变体的效果是斯特恩菌株的10至1000倍。
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本文引用的文献
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