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猴子的脑震荡:一种实验模型。

Cerebral concussion in the monkey: an experimental model.

作者信息

Ommaya A K, Hirsch A E, Flamm E S, Mahone R H

出版信息

Science. 1966 Jul 8;153(3732):211-2. doi: 10.1126/science.153.3732.211.

DOI:10.1126/science.153.3732.211
PMID:4957321
Abstract

A statistically significant experimental model has been developed for reproducing head injury by impact in the monkey. Results with 80 monkeys subjected to occipital impact under specified conditions ( duration of phenomena, 1 to 10 milliseconds) enable the construction of curves relating the production of experimental cerebral concussion in 10, 50, and 90 percent of the monkeys to the average impulse of the blow in pounds-seconds, as well as to the average linear acceleration of the head. These curves are proposed as a baseline from which blows to various parts of the head, as well as nonimpacting impulsive loads, can be studied under various conditions of protection and according to varioucs time regimes.

摘要

已经建立了一个具有统计学意义的实验模型,用于通过撞击在猴子身上再现头部损伤。在特定条件下(现象持续时间为1至10毫秒)对80只猴子进行枕部撞击的结果,使得能够构建曲线,将10%、50%和90%的猴子发生实验性脑震荡与以磅 - 秒为单位的打击平均冲量以及头部的平均线性加速度联系起来。这些曲线被提议作为一个基线,据此可以在各种保护条件下并根据各种时间模式研究对头部不同部位的打击以及非撞击性脉冲载荷。

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1
Cerebral concussion in the monkey: an experimental model.猴子的脑震荡:一种实验模型。
Science. 1966 Jul 8;153(3732):211-2. doi: 10.1126/science.153.3732.211.
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Experimental head injury & concussion in monkey using pure linear acceleration impact.使用纯线性加速度撞击对猴子进行实验性头部损伤和脑震荡。
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[Experimental head injury in monkeys using rotational acceleration impact (author's transl)].
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[Early pathophysiological findings in experimental concussion in rabbits].[兔实验性脑震荡的早期病理生理发现]
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