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胎盘早剥中的休克(作者译)

[Shock in abruptio placentae (author's transl)].

作者信息

Bourdais A, Le Bris H, Wery M A, Jaud V, Pique G, Varieras G, Richard A, Barnaud P

出版信息

Anesth Analg (Paris). 1979 May-Jun;36(5-6):207-14.

PMID:496042
Abstract

In sixty abruptions of the placenta observed during eighteen months, a severe condition of shock was observed in thirty per cent of patients. This shock state is seen during the abruption or after delivery. It's essentially a question of hemorrhagic shock, the importance of hemorrhagy being often underestimated, if the drop of blood pressure and blood losses are only estimated. The measurement of central venous pressure and the research of metabolic acidosis are better indexes of shock. This shock is associated with hypofibrinogenaemia and with other symptoms of disseminated intra-vascular coagulation. Fibrinolysis is rarely observed (3 times). Presence of fibrin degradation products is frequent. Renal complications are observed only in 1/6 of cases, but are frequently severe (one case of renal cortical necrosis). Heparinotherapy does not confirm the hope be suscited and seems to be a frequent source of ehmorrhagic complications in African women. Perfusion of fibrinogen, if useful, can be another source of complications. Rapid transfusion is the more effective treatment of abruption placenta and probably the less dangerous with strict control of the central venous pressure.

摘要

在18个月内观察到的60例胎盘早剥病例中,30%的患者出现了严重的休克状态。这种休克状态在胎盘早剥期间或分娩后出现。这本质上是一个失血性休克的问题,如果仅估计血压下降和失血情况,出血的重要性往往被低估。中心静脉压的测量和代谢性酸中毒的检测是更好的休克指标。这种休克与低纤维蛋白原血症以及其他弥散性血管内凝血症状相关。纤维蛋白溶解很少见(3例)。纤维蛋白降解产物很常见。仅1/6的病例观察到肾脏并发症,但通常很严重(1例肾皮质坏死)。肝素疗法并未带来预期的效果,而且似乎是非洲女性出血并发症的常见原因。输注纤维蛋白原即便有用,也可能是另一个并发症来源。快速输血是治疗胎盘早剥更有效的方法,并且在严格控制中心静脉压的情况下可能是危险性最小的方法。

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