Tannenberg A E
Clin Exp Immunol. 1967 Jan;2(1):133-7.
Exposure of white New Zealand rabbits in the immediate post-natal period to heterologous tissue antigens appeared to induce tolerance as judged by immunodiffusion. However, immunofluorescence tests showed that the animals had in fact developed certain tissue-specific and human-specific antibodies, establishing that immunodiffusion is an inadequate method for demonstrating antibodies to tissue antigens.
通过免疫扩散判断,在出生后即刻将白色新西兰兔暴露于异种组织抗原似乎可诱导耐受性。然而,免疫荧光试验表明,这些动物实际上已产生了某些组织特异性和人特异性抗体,这表明免疫扩散并非检测针对组织抗原抗体的充分方法。