Canalis R F, Hemenway W G, Ward P H
Ann Otol Rhinol Laryngol. 1979 Sep-Oct;88(5 Pt 1):642-6. doi: 10.1177/000348947908800509.
Recent studies on the fate of pedicle osteocutaneous grafts have shown that they remain viable and may be actively involved in the mechanics of bone repair. This communication reports on a series of experiments aimed to clarify the role of periosteum in the survival of pedicle-assisted bone grafts. Osteocutaneous grafts were developed in dogs in such a manner as to isolate the implant from normal recipient bone. Free bone grafts were used as controls and a group of pedicle periosteal grafts were studied as potential sources of bone formation. Specimens were evaluated at regular intervals over a 40-week period. The pedicle bone grafts maintained their viability and developed vigorous osteoneogenesis. The process was progressive and eventually resulted in partial substitution of the original graft by new bone of periosteal origin. The free bone grafts were resorbed and no bone formation was obtained in pedicle periosteum specimens. The study provides clear evidence that under experimental conditions no bone contact is needed to maintain the viability of pedicle osteocutaneous grafts. It also shows that the periosteum has the leading role in the restructuring process of these grafts.
近期关于带蒂骨皮瓣转归的研究表明，它们能够保持存活，并可能积极参与骨修复的力学过程。本通讯报道了一系列旨在阐明骨膜在带蒂辅助骨移植存活中作用的实验。在犬身上制作骨皮瓣，以使植入物与正常受区骨隔离。游离骨移植用作对照，并研究一组带蒂骨膜移植作为潜在的骨形成来源。在40周的时间内定期对标本进行评估。带蒂骨移植保持其活力并形成旺盛的骨生成。这个过程是渐进的，最终导致原始移植被骨膜来源的新骨部分替代。游离骨移植被吸收，带蒂骨膜标本中未获得骨形成。该研究提供了明确的证据，即在实验条件下，维持带蒂骨皮瓣的存活不需要骨接触。它还表明，骨膜在这些移植的重建过程中起主导作用。
