Webster D B, Webster M
Ann Otol Rhinol Laryngol. 1979 Sep-Oct;88(5 Pt 1):684-8. doi: 10.1177/000348947908800515.
Both postnatal auditory deprivation and experimentally produced conductive hearing losses in mice result in incomplete maturation of most brain stem auditory neurons. The affected groups are: octopus cell, globular cell, small spherical cell, and large spherical cell groups in ventral cochlear nuclei; and the lateral superior olive and medial nucleus of the trapezoid body of the superior olivary complex. When 45 days of auditory deprivation are followed by 45 days of normal acoustic stimulation, there is incomplete maturation of neurons in: multipolar cell, globular cell, small spherical cell, and large spherical cell groups in ventral cochlear nuclei; lateral superior olive and medial nucleus of trapezoid body in superior olivary complex; and central nucleus of inferior colliculus. A critical period exists when adequate sound stimulation is needed for full development of these neurons.
出生后的听觉剥夺以及实验诱导的小鼠传导性听力损失，都会导致大多数脑干听觉神经元成熟不完全。受影响的群体包括：蜗腹侧核中的章鱼细胞、球状细胞、小球状细胞和大球状细胞群；以及上橄榄复合体的外侧上橄榄核和斜方体内侧核。当45天的听觉剥夺之后接着45天的正常声刺激时，蜗腹侧核中的多极细胞、球状细胞、小球状细胞和大球状细胞群；上橄榄复合体中的外侧上橄榄核和斜方体内侧核；以及下丘中央核的神经元会出现成熟不完全的情况。这些神经元的充分发育需要足够的声音刺激，这存在一个关键期。
