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结核分枝杆菌在深层培养中的自溶和二次生长

Autolysis and secondary growth of Mycobacterium tuberculosis in submerged culture.

作者信息

Wayne L G, Diaz G A

出版信息

J Bacteriol. 1967 Apr;93(4):1374-81. doi: 10.1128/jb.93.4.1374-1381.1967.

DOI:10.1128/jb.93.4.1374-1381.1967
PMID:4962059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC276611/
Abstract

Mycobacterium tuberculosis has been found to exhibit autolysis and spontaneous secondary growth in modified Sauton medium. The phenomenon is a function of high glycerol concentration of the medium and limitation of air in test tubes. It is not a function of depletion of nutrients and is probably not a manifestation of lysogeny or spheroplast formation. The cycle of growth, autolysis, and secondary growth is related to development of lethal conditions during a period of severe oxygen limitation followed by a metabolic change associated with slower depletion of glycerol.

摘要

已发现结核分枝杆菌在改良的苏通培养基中会出现自溶和自发二次生长现象。该现象是培养基中甘油浓度过高以及试管内空气受限的结果。它并非营养物质耗尽所致，可能也不是溶原性或原生质球形成的表现。生长、自溶和二次生长的循环与在严重氧气受限期间致死条件的发展有关，随后是与甘油消耗减缓相关的代谢变化。

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Autolysis and secondary growth of Mycobacterium tuberculosis in submerged culture.结核分枝杆菌在深层培养中的自溶和二次生长
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本文引用的文献

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Kinetics of Utilization of Organic Compounds in the Growth of Mycobacterium tuberculosis.结核分枝杆菌生长过程中有机化合物利用的动力学
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The growth of Mycobacterium tuberculosis as a function of its nutrients.结核分枝杆菌的生长与其营养物质的关系。
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THE MEASUREMENT OF GLYCEROL IN THE PRESENCE OF CITRATE.在柠檬酸盐存在的情况下甘油的测定
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FORMATION OF SPHEROPLASTS OF MYCOBACTERIUM TUBERCULOSIS BY LYSOZYME.溶菌酶诱导结核分枝杆菌原生质球的形成
Proc Soc Exp Biol Med. 1963 Oct;114:43-7. doi: 10.3181/00379727-114-28580.
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Effect of tween 80 and serum on the interaction of mycobacteriophage D-29 with certain mycobacterial species.
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Biochemical differentiation of Mycobacterium tuberculosis grown in vivo and in vitro.体内和体外培养的结核分枝杆菌的生化分化
J Bacteriol. 1956 Aug;72(2):132-41. doi: 10.1128/jb.72.2.132-141.1956.
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Tetrazolium reduction by tubercle bacilli.结核杆菌对四氮唑的还原作用。
J Lab Clin Med. 1955 Oct;46(4):608-14.
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Studies on the growth of Mycobacteria. I. The occurrence of arithmetic linear growth.分枝杆菌生长的研究。I. 算术线性生长的发生情况
Am Rev Tuberc. 1952 Dec;66(6):758-61. doi: 10.1164/art.1952.66.6.758.