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[坏疽性脓皮病与血液病。三例报告(作者译)]

[Pyoderma gangrenosum and haemopathy. Report of three cases (author's transl)].

作者信息

Barrière H, Litoux P, Stalder J F, Barrier J

出版信息

Ann Dermatol Venereol. 1979 May;106(5):427-35.

PMID:496206
Abstract

The authors report three personal cases of phagedenic pyoderma associated with hemopathy. Studying twenty-five other cases, described in the reviews, the question can be debated on three levels: 1) The clinical characteristics of hemopathic pyoderma remain non-specific. However blisters, pustules, and even vegetating lesions occur very often; 2) the etiology of hemopathy is subject to change; acute leukaemia or myeloproliferation syndrome. During the polyglobulars associated with pyoderma, anemia and myelofibrosis appear quite constantly; 3) finally on the pathogenic level, the recent works tend towards the hypothesis of a damage in the functioning of the polymorphonuclears hence displaying the increase in the inflammation during phagedenic pyoderma.

摘要

作者报告了三例与血液病相关的坏疽性脓皮病的个人病例。在研究综述中描述的其他25个病例时,这个问题可以在三个层面上进行探讨:1)血液病性脓皮病的临床特征仍然是非特异性的。然而,水疱、脓疱甚至增殖性病变非常常见;2)血液病的病因可能会发生变化;急性白血病或骨髓增殖综合征。在与脓皮病相关的红细胞增多症期间,贫血和骨髓纤维化相当常见;3)最后在发病机制层面,最近的研究倾向于多核白细胞功能受损的假说,因此在坏疽性脓皮病期间炎症会增加。

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