Fortier P, Maylin C, Gerbaulet A, Zeller J, Touraine R
Ann Dermatol Venereol. 1979 May;106(5):465-8.
87 cases of epidermoid carcinoma of the penis treated by Ir 192 interstitial radiotherapy are studied. The 5 years survival rate, estimated on a 51 patients group, is 61 p. 100. Among these 51 patients, 12 had a local recurrence. The post-radiotherapy early reaction is estimated on a 79 patients group, with a mean duration of 3, 4 months. The early reaction is correlated to tumor size and not correlated to number of radio-active lines. The later dermatologic evolution is studied in 59 patients. In 22 cases, the scar remained supple, without any further local change. Local changes occurring in the 37 other cases are studied in their clinical aspect, signification and frequency. Of 34 patients followed longer than 40 months, 14 had local complications with 4 cases of local recurrence. The carcinologic reliability of this method is similar to that by surgery. It seems however it must be restricted to tumors limited to glans penis.
对87例采用铱192组织间放疗治疗的阴茎表皮样癌患者进行了研究。在一个由51例患者组成的队列中评估的5年生存率为61%。在这51例患者中，有12例出现局部复发。在一个由79例患者组成的队列中评估了放疗后的早期反应，平均持续时间为3.4个月。早期反应与肿瘤大小相关，与放射源数量无关。对59例患者的后期皮肤演变情况进行了研究。在22例患者中，瘢痕保持柔软，无任何进一步的局部变化。对其他37例患者出现的局部变化进行了临床特征、意义及发生率方面的研究。在34例随访时间超过40个月的患者中，14例出现局部并发症，其中4例局部复发。该方法在肿瘤学方面的可靠性与手术相似。然而，它似乎必须仅限于局限于阴茎头的肿瘤。
