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1
Post-synaptic effects of cortical stimulation on forelimb motoneurones in the baboon.狒狒大脑皮层刺激对前肢运动神经元的突触后效应。
J Physiol. 1967 Aug;191(3):673-90. doi: 10.1113/jphysiol.1967.sp008274.
2
Responses of the pyramidal tract to stimulation of the baboon's motor cortex.锥体束对狒狒运动皮层刺激的反应。
J Physiol. 1967 Aug;191(3):653-72. doi: 10.1113/jphysiol.1967.sp008273.
3
Projections of pyramidal tract cells to alpha-motoneurones innervating hind-limb muscles in the monkey.猴子中锥体束细胞向支配后肢肌肉的α运动神经元的投射。
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4
The distribution of monosynaptic excitation from the pyramidal tract and from primary spindle afferents to motoneurones of the baboon's hand and forearm.从锥体束和初级肌梭传入纤维到狒狒手部和前臂运动神经元的单突触兴奋分布。
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5
Corticomotoneuronal organization. Projection from the arm area of the baboon's motor cortex.皮质脊髓运动神经元组织。狒狒运动皮层臂区的投射。
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6
Corticospinal Inputs to Primate Motoneurons Innervating the Forelimb from Two Divisions of Primary Motor Cortex and Area 3a.来自初级运动皮层两个分区和3a区的支配灵长类动物前肢运动神经元的皮质脊髓输入。
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J Physiol. 1968 Mar;195(2):419-49. doi: 10.1113/jphysiol.1968.sp008466.
8
Cortical and long spinal actions on lumbosacral motoneurones in the cat.猫中皮质和长脊髓对腰骶运动神经元的作用。
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9
Long-term facilitation of excitatory synaptic transmission in single motor cortical neurones of the cat produced by repetitive pairing of synaptic potentials and action potentials following intracellular stimulation.在细胞内刺激后,通过突触电位和动作电位的重复配对,在猫的单个运动皮层神经元中产生兴奋性突触传递的长期易化。
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10
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Exp Brain Res. 1976 Dec 22;26(5):509-19. doi: 10.1007/BF00238824.

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The distribution of monosynaptic excitation from the pyramidal tract and from primary spindle afferents to motoneurones of the baboon's hand and forearm.从锥体束和初级肌梭传入纤维到狒狒手部和前臂运动神经元的单突触兴奋分布。
J Physiol. 1968 Sep;198(1):145-66. doi: 10.1113/jphysiol.1968.sp008598.
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Recruitment of motor units in response to transcranial magnetic stimulation in man.人类对经颅磁刺激产生反应时运动单位的募集。
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7
Evidence favouring different descending pathways to soleus motoneurones activated by magnetic brain stimulation in man.支持人类大脑磁刺激激活比目鱼肌运动神经元的不同下行通路的证据。
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8
Responses of the pyramidal tract to stimulation of the baboon's motor cortex.锥体束对狒狒运动皮层刺激的反应。
J Physiol. 1967 Aug;191(3):653-72. doi: 10.1113/jphysiol.1967.sp008273.
9
The short-latency projection from the baboon's motor cortex to fusimotor neurones of the forearm and hand.从狒狒运动皮层到前臂和手部肌梭运动神经元的短潜伏期投射。
J Physiol. 1971 Jul;216(2):257-79. doi: 10.1113/jphysiol.1971.sp009524.
10
Lack of involvement of fusimotor activation in movements of the foot produced by electrical stimulation of monkey cerebral cortex.电刺激猴大脑皮层所引发的足部运动中,肌梭运动激活未参与其中。
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本文引用的文献

1
Impulses in the pyramidal tract.锥体束中的冲动。
J Physiol. 1939 Dec 14;97(2):153-99. doi: 10.1113/jphysiol.1939.sp003798.
2
Minimal synaptic actions of pyramidal impulses on some alpha motoneurones of the baboon's hand and forearm.狒狒手部和前臂的一些α运动神经元上锥体冲动的最小突触作用
J Physiol. 1962 Apr;161(1):91-111. doi: 10.1113/jphysiol.1962.sp006875.
3
Precentral facilitation and inhibition of spinal motoneurons.中央前回对脊髓运动神经元的易化和抑制作用。
J Neurophysiol. 1960 Mar;23:154-70. doi: 10.1152/jn.1960.23.2.154.
4
COMPARISON OF MOTOR CORTEX INFLUENCES UPON VARIOUS HIND-LIMB MOTONEURONS IN PYRAMIDAL CATS AND PRIMATES.锥体猫和灵长类动物中运动皮层对各种后肢运动神经元影响的比较
J Neurophysiol. 1965 Mar;28:398-412. doi: 10.1152/jn.1965.28.2.398.
5
THE PYRAMIDAL PROJECTION TO MOTONEURONES OF SOME MUSCLE GROUPS OF THE BABOON'S FORELIMB.狒狒前肢某些肌肉群向运动神经元的锥体投射
Prog Brain Res. 1964;12:222-45. doi: 10.1016/s0079-6123(08)60625-1.
6
A comparison of motor cortex effects on slow and fast muscle innervations in the monkey.猴子运动皮层对慢肌和快肌神经支配的影响比较。
Exp Neurol. 1963 Apr;7:327-41. doi: 10.1016/0014-4886(63)90079-7.
7
Selective excitation of corticofugal neurones by surface-anodal stimulation of the baboon's motor cortex.通过对狒狒运动皮层进行表面阳极刺激来选择性激发皮质离心神经元。
J Physiol. 1962 Apr;161(1):73-90. doi: 10.1113/jphysiol.1962.sp006874.
8
Intracellular potentials recorded from motoneurons following precentral gyrus stimulation in primate.在灵长类动物中央前回刺激后从运动神经元记录到的细胞内电位。
J Neurophysiol. 1961 Jan;24:91-100. doi: 10.1152/jn.1961.24.1.91.
9
Single and multiple-unit analysis of cortical stage of pyramidal tract activation.锥体束激活皮层阶段的单单位和多单位分析。
J Neurophysiol. 1954 Jul;17(4):345-63. doi: 10.1152/jn.1954.17.4.345.
10
Differential patterns of activation of the pyramidal system elicited by surface anodal and cathodal cortical stimulation.表面阳极和阴极皮层刺激引发的锥体系统激活的差异模式。
J Neurophysiol. 1966 Jul;29(4):547-64. doi: 10.1152/jn.1966.29.4.547.

狒狒大脑皮层刺激对前肢运动神经元的突触后效应。

Post-synaptic effects of cortical stimulation on forelimb motoneurones in the baboon.

作者信息

Kernell D, Chien-Ping W

出版信息

J Physiol. 1967 Aug;191(3):673-90. doi: 10.1113/jphysiol.1967.sp008274.

DOI:10.1113/jphysiol.1967.sp008274
PMID:4963873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1365498/
Abstract
  1. The arm area of the baboon's precentral motor cortex was stimulated by brief surface-anodal pulses, and the post-synaptic potentials elicited in contralateral forelimb motoneurones were studied by intracellular recording.2. Strong cortical stimuli elicited a rapid series of excitatory and, in some cells, inhibitory post-synaptic potentials (EPSPs and IPSPs respectively). Comparisons with the simultaneously recorded response of the pyramidal tract indicated that these post-synaptic potentials were due to a repetitive discharge of fast pyramidal fibres. Thus, the later synaptic events were mostly due to a repetition of the early monosynaptic EPSP and early IPSP respectively.3. Inhibition was seen more often in cells whose monosynaptic EPSP had a small maximal size than in those whose monosynaptic EPSP was larger. The net depolarization produced by a strong cortical stimulus was related to the maximal size of the early monosynaptic EPSP.4. In the Discussion, an interpretation is suggested for previous findings concerning the spinal distribution of late synaptic effects elicited by cortical stimulation.
摘要
  1. 用短暂的表面阳极脉冲刺激狒狒中央前回运动皮层的臂区,通过细胞内记录研究对侧前肢运动神经元诱发的突触后电位。

  2. 强皮层刺激引发了一系列快速的兴奋性突触后电位,在某些细胞中还引发了抑制性突触后电位(分别为兴奋性突触后电位和抑制性突触后电位)。与同时记录的锥体束反应进行比较表明,这些突触后电位是由于快速锥体纤维的重复放电所致。因此,后期的突触事件大多分别是早期单突触兴奋性突触后电位和早期抑制性突触后电位重复的结果。

  3. 在单突触兴奋性突触后电位最大幅度较小的细胞中比在单突触兴奋性突触后电位较大的细胞中更常观察到抑制现象。强皮层刺激产生的净去极化与早期单突触兴奋性突触后电位的最大幅度有关。

  4. 在讨论中,对先前关于皮层刺激诱发的晚期突触效应在脊髓分布的研究结果提出了一种解释。