Marks J S, Hardinge K
Ann Rheum Dis. 1979 Aug;38(4):332-6. doi: 10.1136/ard.38.4.332.
The clinical and radiographic features of hip disease in 76 patients with definite ankylosing spondylitis have been studied. Symptomatic hip involvement occurred late in the course of the disease, with a mean delay after the onset of 12 years in males and 7 years in females. Patients with disease onset before the age of 20 developed hip symptoms at an earlier stage. Associated diseases included uveitis (13%), colitis (4%). Bilateral concentric loss of hip joint space with a relatively undeformed femoral head was the commonest radiological change (61%). Localised loss of joint space at the upper pole (16%) was associated with femoral head destruction and a greater degree of osteophytosis, suggesting coincidental or secondary osteoarthrosis. Bony ankylosis of the hips (10%) was present only in women, and the absence of osteophytes, cysts, and bone lesions of the iliac crests and ischial rami suggests that it is a distinct radiographic manifestation of female ankylosing spondylitis.
对76例确诊强直性脊柱炎患者的髋关节疾病临床及影像学特征进行了研究。有症状的髋关节受累在疾病进程中出现较晚，男性发病后平均延迟12年，女性为7年。20岁前发病的患者髋关节症状出现较早。相关疾病包括葡萄膜炎（13%）、结肠炎（4%）。髋关节间隙双侧同心性变窄且股骨头相对未变形是最常见的放射学改变（61%）。上极关节间隙局限性变窄（16%）与股骨头破坏及更严重的骨赘形成有关，提示合并或继发性骨关节炎。髋关节骨性强直（10%）仅见于女性，且髂嵴和坐骨支无骨赘、囊肿及骨质破坏，提示这是女性强直性脊柱炎一种独特的放射学表现。
