Xenakis C, Holtmann W
Arch Psychiatr Nervenkr (1970). 1979 Jul 4;227(1):39-47. doi: 10.1007/BF00585676.
Our paper is concerned with considerations of pain physiology in pyrovasy and with neuropharmacological effects of the Opiate antagonist Naloxone. These considerations explain the relationship of analgesia and hypersthesia with stress induced behavior and states of consciousness. Apart from psychophysiological aspects we can distinguish from a biochemical and neurophysiological point of view two mechanisms of pain perception in pyrovates: 1. Certain mechanical stimuli brought about by the individual running technique of the pyrovate cause convergence of noxis and non-noxic afferent impulses as well as central inhibition of the effect of noxic stimuli. 2. The long stressful period of preparations induces a temporary surplus of Endorphins elevating the pain threshold.
我们的论文关注烧伤中的疼痛生理学以及阿片类拮抗剂纳洛酮的神经药理学作用。这些考量解释了镇痛和感觉过敏与应激诱导行为及意识状态之间的关系。除了心理生理学方面,从生化和神经生理学角度来看,我们可以区分烧伤中疼痛感知的两种机制:1. 烧伤患者个体跑步技术所产生的某些机械刺激导致伤害性和非伤害性传入冲动的汇聚以及对伤害性刺激效应的中枢抑制。2. 长时间的应激准备期会诱导内啡肽暂时过剩,从而提高痛阈。