阿片类拮抗剂纳洛酮未能改变催眠性镇痛效果。
Failure of the opiate antagonist naloxone to modify hypnotic analgesia.
作者信息
Goldstein A, Hilgard E R
出版信息
Proc Natl Acad Sci U S A. 1975 Jun;72(6):2041-3. doi: 10.1073/pnas.72.6.2041.
Abstract
Hypnotic analgesia in some respects resembles opiate analgesia. We tested the hypothesis that some features of hypnotic analgesia are mediated through neuronal pathways activating specific opiate receptors in brain. The opiate antagonist naloxone had no effect on hypnotic analgesia in three subjects. Thus, the hypothesis was not confirmed.
摘要
催眠镇痛在某些方面类似于阿片类镇痛。我们检验了这样一个假说，即催眠镇痛的某些特征是通过激活大脑中特定阿片受体的神经通路介导的。阿片拮抗剂纳洛酮对三名受试者的催眠镇痛没有影响。因此，该假说未得到证实。
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