脑膜炎球菌的快速磺胺纸片敏感试验
Rapid sulfonamide disc sensitivity test for meningococci.
作者信息
Bennett J V, Camp H M, Eickhoff T C
出版信息
Appl Microbiol. 1968 Jul;16(7):1056-60. doi: 10.1128/am.16.7.1056-1060.1968.
Abstract
Minimal inhibitory concentrations (MIC) of 90 strains of Neisseria meningitidis were determined by a plate dilution technique that employed twofold changes in concentrations of sulfadiazine. The geometric mean of three MIC determinations on each strain was correlated with inhibition zones produced by a 300-mug sulfathiazole disc. The linear relationship between the logarithm of the geometric mean MIC values and the zone diameters was highly significant. Strains were separated into sensitive and resistant populations by both test procedures. Quantitative criteria for interpreting the sensitivity of a strain by the disc test were established.
摘要
采用平板稀释技术，通过使磺胺嘧啶浓度呈两倍变化，测定了90株脑膜炎奈瑟菌的最低抑菌浓度（MIC）。对每株菌进行三次MIC测定的几何平均值，与300微克磺胺噻唑纸片产生的抑菌圈相关。几何平均MIC值的对数与抑菌圈直径之间的线性关系非常显著。通过这两种检测程序将菌株分为敏感和耐药群体。建立了用纸片试验解释菌株敏感性的定量标准。
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本文引用的文献
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LACTOSE-FERMENTING ORGANISMS RESEMBLING NEISSERIA MENINGITIDIS.类似脑膜炎奈瑟菌的乳糖发酵菌。
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