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中枢神经系统正常组织和脱髓鞘组织中的缩醛磷脂酶活性。

Plasmalogenase activity in normal and demyelinating tissue of the central nervous system.

作者信息

Ansell G B, Spanner S

出版信息

Biochem J. 1968 Jun;108(2):207-9. doi: 10.1042/bj1080207.

DOI:10.1042/bj1080207
PMID:4969863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1198794/
Abstract
  1. The plasmalogenase activity of brain was found to be associated with the white matter but was absent from myelin fractions. 2. Increased enzyme activity was found in demyelinating spinal cords from vitamin B(12)-deficient monkeys and in white matter from a patient with multiple sclerosis.
摘要
  1. 发现脑的缩醛磷脂酶活性与白质有关,但在髓磷脂组分中不存在。2. 在维生素B12缺乏的猴子的脱髓鞘脊髓以及一名多发性硬化症患者的白质中发现酶活性增加。

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Plasmalogenase activity in normal and demyelinating tissue of the central nervous system.中枢神经系统正常组织和脱髓鞘组织中的缩醛磷脂酶活性。
Biochem J. 1968 Jun;108(2):207-9. doi: 10.1042/bj1080207.
2
Plasmalogenase is elevated in early demyelinating lesions.在早期脱髓鞘病变中,缩醛磷脂酶水平升高。
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Activity of hydrolytic enzymes in a case of subacute multiple sclerosis.亚急性多发性硬化症病例中水解酶的活性
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Eur Neurol. 1973;9(1):1-20. doi: 10.1159/000114197.
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Front Cell Dev Biol. 2022 Aug 31;10:946393. doi: 10.3389/fcell.2022.946393. eCollection 2022.
2
Nuclear lipid mediators: Role of nuclear sphingolipids and sphingosine-1-phosphate signaling in epigenetic regulation of inflammation and gene expression.核脂质介质:核鞘脂类和鞘氨醇 1-磷酸信号在炎症和基因表达的表观遗传调控中的作用。
J Cell Biochem. 2018 Aug;119(8):6337-6353. doi: 10.1002/jcb.26707. Epub 2018 May 8.
3
Plasmalogenase and phospholipase A1, A2, and L1 activities in white matter in canine distemper virus-associated demyelinating encephalomyelitis.
Acta Neuropathol. 1980;49(1):13-8. doi: 10.1007/BF00692214.
4
Comparison of two molecular species of ethanolamine plasmalogen in multiple sclerosis and normal myelin.多发性硬化症和正常髓鞘中乙醇胺缩醛磷脂两种分子种类的比较。
Neurochem Res. 1982 Aug;7(8):953-64. doi: 10.1007/BF00965135.
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Investigations of the lipid metabolism of the white matter in multiple sclerosis: changes in glycero-phosphatides and lipid-splitting enzymes.多发性硬化症中白质脂质代谢的研究:甘油磷脂和脂质分解酶的变化
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Acta Neuropathol. 1972;22(4):288-94. doi: 10.1007/BF00809240.
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Gas liquid chromatographic analysis of sphingosine bases in sphingolipids of human normal and multiple sclerosis cerebral white matter.人正常及多发性硬化脑白质鞘脂中鞘氨醇碱基的气相色谱分析
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[On the activity of phospholipase A2 compared with 1-alk-1'-enyl-2-acyl- and 1-alkyl-2-acyl-glycerophosphatides in multiple sclerosis (author's transl)].
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本文引用的文献

1
THE MAGNESIUM-ION-DEPENDENT CLEAVAGE OF THE VINYL ETHER LINKAGE OF BRAIN ETHANOLAMINE PLASMALOGEN.脑乙醇胺缩醛磷脂乙烯醚键的镁离子依赖性裂解
Biochem J. 1965 Jan;94(1):252-8. doi: 10.1042/bj0940252.
2
ALTERATIONS IN MYELIN FATTY ACIDS AND PLASMALOGENS IN MULTIPLE SCLEROSIS.多发性硬化症中髓鞘脂肪酸和缩醛磷脂的改变
Ann N Y Acad Sci. 1965 Mar 31;122:405-16. doi: 10.1111/j.1749-6632.1965.tb20223.x.
3
THE ALKALINE HYDROLYSIS OF THE ETHANOLAMINE PLASMALOGEN OF BRAIN TISSUE.脑组织乙醇胺缩醛磷脂的碱性水解
J Neurochem. 1963 Dec;10:941-5. doi: 10.1111/j.1471-4159.1963.tb11921.x.
4
The formation of lysophosphatides from di-acyl phosphatides by brain preparations.脑提取物将二酰基磷脂转化为溶血磷脂的过程。
J Neurochem. 1962 Nov-Dec;9:545-54. doi: 10.1111/j.1471-4159.1962.tb04209.x.
5
The biochemistry of plasmalogens. I. Isolation and characterization of phosphatidal choline, a pure native plasmalogen.缩醛磷脂的生物化学。I. 磷脂酰胆碱的分离与特性鉴定,一种纯天然缩醛磷脂。
J Biol Chem. 1962 Feb;237:329-33.
6
Improvements in the method of determining individual phospholipids in a complex mixture by successive chemical hydrolyses.通过连续化学水解测定复杂混合物中单个磷脂方法的改进。
Biochem J. 1962 Sep;84(3):497-501. doi: 10.1042/bj0840497.
7
Cerebral lipids in multiple sclerosis.多发性硬化症中的脑脂质
J Neurochem. 1962 Jul-Aug;9:427-32. doi: 10.1111/j.1471-4159.1962.tb09470.x.
8
Proteinase activity of nervous tissues in organo-phosphorus compound poisoning.有机磷化合物中毒时神经组织的蛋白酶活性
J Neurochem. 1961 Aug;7:317-20. doi: 10.1111/j.1471-4159.1961.tb13520.x.
9
Clearing action of lysolecithin on brain homogenates.溶血卵磷脂对脑匀浆的清除作用。
Nature. 1957 Sep 28;180(4587):660-1. doi: 10.1038/180660a0.
10
The metabolism of labelled ethanolamine in the brain of the rat in vivo.大鼠脑内标记乙醇胺的体内代谢
J Neurochem. 1967 Sep;14(9):873-85. doi: 10.1111/j.1471-4159.1967.tb09576.x.