Hunter J M, Jones R S, Lamplugh G, Utting J E
Br J Anaesth. 1979 Aug;51(8):725-31. doi: 10.1093/bja/51.8.725.
Hypocapnia was induced in dogs lightly anaesthetized with nitrous oxide and fentanyl. Measurements were made of estimated renal plasma flow (ERPF), glomerular filtration rate, vascular resistance and urine production. During the (short) duration of the experiments hypocapnia was found to be associated with ERPF twice that during normocapnia. Glomerular filtration rate and urine output were increased by hypocapnia in an approximately similar proportion, whilst renal vascular resistance halved. Though some of the experimental animals had a degree of metabolic acidosis this was thought not to have greatly influenced the results.
用一氧化二氮和芬太尼轻度麻醉犬只以诱导低碳酸血症。测量了估计的肾血浆流量（ERPF）、肾小球滤过率、血管阻力和尿量。在实验的（短暂）期间，发现低碳酸血症时的ERPF是正常碳酸血症时的两倍。低碳酸血症使肾小球滤过率和尿量增加的比例大致相似，而肾血管阻力减半。尽管一些实验动物有一定程度的代谢性酸中毒，但认为这对结果没有太大影响。
