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Activation of lymphocytes.

作者信息

Pulvertaft R J, Pulvertaft I

出版信息

J Clin Pathol. 1967 Nov;20(6):795-805. doi: 10.1136/jcp.20.6.795.

DOI:10.1136/jcp.20.6.795
PMID:4972989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC473597/
Abstract

The technique involved in studying the activation of lymphocytes in the resting form, and their recognition as dividing and functional cells was studied, using phase contrast and agar as well as fluid culture. Standardization of technical methods was found to be essential, and the effect of variables was studied. Lymphocytes from human umbilical cord vein blood were found to be spontaneously activated. Infestation by microfilaria either diminished or entirely inhibited activation. The significance of lymphocytic cohesion was considered and the formation of colonies of activated lymphocytes on agar is described. The effects of non-human vertebrate lymphocytes and of human cells other than lymphocytes were studied. Spontaneous activation of abnormal lymphocytes was noted.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/b069f357d1d8/jclinpath00371-0010-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/d487aee9d1cf/jclinpath00371-0003-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/fcdf571582dd/jclinpath00371-0003-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/1827edcaf3ff/jclinpath00371-0003-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/b128f7f4b358/jclinpath00371-0004-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/998d3bc0c2c7/jclinpath00371-0004-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/c86d7d021c9e/jclinpath00371-0005-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/fe50781c3a68/jclinpath00371-0005-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/e24997544600/jclinpath00371-0005-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/dd475c0649c0/jclinpath00371-0010-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/b069f357d1d8/jclinpath00371-0010-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/d487aee9d1cf/jclinpath00371-0003-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/fcdf571582dd/jclinpath00371-0003-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/1827edcaf3ff/jclinpath00371-0003-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/b128f7f4b358/jclinpath00371-0004-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/998d3bc0c2c7/jclinpath00371-0004-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/c86d7d021c9e/jclinpath00371-0005-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/fe50781c3a68/jclinpath00371-0005-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/e24997544600/jclinpath00371-0005-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/dd475c0649c0/jclinpath00371-0010-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2295/473597/b069f357d1d8/jclinpath00371-0010-b.jpg

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Activation of lymphocytes.
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Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9954-9959. doi: 10.1073/pnas.1707098114. Epub 2017 Aug 28.
2
DNA synthesis in mixed cultures of rat leukocytes and allogeneic dissociated skin cells.大鼠白细胞与同种异体解离皮肤细胞混合培养物中的DNA合成。
Proc Natl Acad Sci U S A. 1971 Jun;68(6):1165-8. doi: 10.1073/pnas.68.6.1165.

本文引用的文献

1
PHYTOHAEMAGGLUTININ IN RELATION TO BURKITT'S TUMOUR. (AFRICAN LYMPHOMA).植物血凝素与伯基特氏瘤（非洲淋巴瘤）的关系
Lancet. 1964 Sep 12;2(7359):552-4. doi: 10.1016/s0140-6736(64)90618-x.
2
THE DEVELOPMENT OF LARGE IMMATURE MONONUCLEAR CELLS IN MIXED LEUKOCYTE CULTURES.混合白细胞培养中大型未成熟单核细胞的发育
Blood. 1964 Jan;23:108-16.
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SEPARATION OF VIABLE LYMPHOCYTES FROM HUMAN BLOOD.从人血中分离活淋巴细胞
Lancet. 1964 Feb 29;1(7331):468-9. doi: 10.1016/s0140-6736(64)90799-8.
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Maternofetal passage of leukocytes and platelets in man.人类中白细胞和血小板的母胎通道。
Blood. 1963 Jun;21:665-73.
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Differences between lymphocytes of leukemic and non-leukemic patients with respect to morphologic features, motility, and sensitivity to guinea pig serum.白血病患者与非白血病患者淋巴细胞在形态学特征、运动性及对豚鼠血清敏感性方面的差异。
Blood. 1961 Nov;18:561-71.
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The cytological identity and interrelation of mesenchymal cells of lymphoid tissue.
Ann N Y Acad Sci. 1958 Sep 5;73(1):120-30. doi: 10.1111/j.1749-6632.1959.tb40796.x.
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A factor stimulating DNA synthesis derived from the medium of leukocyte cultures.一种源自白细胞培养基的刺激DNA合成的因子。
Nature. 1965 Nov 20;208(5012):794-5. doi: 10.1038/208794a0.
8
A lymphocyte-stimulating factor produced in vitro.
Nature. 1965 Nov 20;208(5012):795-6. doi: 10.1038/208795a0.
9
Spontaneous "transformation" of lymphocytes from the umbilical-cord vein.
Lancet. 1966 Oct 22;2(7469):892-3. doi: 10.1016/s0140-6736(66)91986-6.