Hayem A, Scharfman A, Laine A, Lebas J, Kopaczewski A
Bull Eur Physiopathol Respir. 1979 Jul-Aug;15(4):611-24.
Six normal subjects, two of whom were heavy smokers, underwent broncho-alveolar and bronchial washings. The aim of our work was to compare the biochemical composition of these fluids. Quantitative measurements of total protein, IgG AND IgA were made, the percentage of IgA 7S among the IgA population was established, an immunoelectrophoretic study was carried out, and glycosidase and protease activities were determined. In a given subject, the bronchial washing always showed more IgA, 11S and more concentrated glycosidase activities than the broncho-alveolar washing; the latter had higher values for IgG and protease activities, the most important being chymotrypsin-like activity. In both fluids, IgA 11S represented the main part of IgA population.
六名正常受试者接受了支气管肺泡灌洗和支气管冲洗，其中两名是重度吸烟者。我们研究的目的是比较这些液体的生化组成。对总蛋白、IgG和IgA进行了定量测量，确定了IgA群体中7S IgA的百分比，进行了免疫电泳研究，并测定了糖苷酶和蛋白酶活性。在给定的受试者中，支气管冲洗液中的IgA、11S和糖苷酶活性总是比支气管肺泡灌洗液中的更高；后者的IgG和蛋白酶活性值更高，其中最重要的是类胰凝乳蛋白酶活性。在两种液体中，11S IgA均占IgA群体的主要部分。
