Smith A L, Satterthwaite H S, Sokoloff L
Science. 1969 Jan 3;163(3862):79-81. doi: 10.1126/science.163.3862.79.
D(m)-beta-hydroxybutyrate dehydrogenase activity is very low in normal adult rat brain; but during fasting it increases severalfold in parallel with the ketosis. The increase may represent part of a mechanism by which the brain adapts to changing patterns of substrate supply during starvation.
D(m)-β-羟丁酸脱氢酶活性在正常成年大鼠脑中非常低;但在禁食期间,它会随着酮症的出现而增加几倍。这种增加可能是大脑在饥饿期间适应底物供应变化模式的一种机制的一部分。