通过乳胶凝集法测定动物对肺炎支原体的抗体反应。

Antibody response of animals to Mycoplasma pneumoniae measured by latex agglutination.

作者信息

Kende M

出版信息

Appl Microbiol. 1969 Feb;17(2):275-9. doi: 10.1128/am.17.2.275-279.1969.

DOI:10.1128/am.17.2.275-279.1969

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC377664/

Abstract

The standardization, application, and usefulness of latex agglutination for Mycoplasma pneumoniae antibody titration were investigated and compared with tetrazolium reduction inhibition and complement fixation. The sera of guinea pigs and monkeys reacted in a specific fashion, whereas rabbit serum required pretreatment to eliminate its nonspecific agglutinin. Human serum given such pretreatment still contained a nonspecific agglutinin. The latex agglutination procedure compared favorably with complement fixation and metabolic inhibition tests for evaluating vaccine antigenicity.

摘要

对用于肺炎支原体抗体滴定的乳胶凝集试验的标准化、应用及实用性进行了研究，并与四氮唑还原抑制试验和补体结合试验进行了比较。豚鼠和猴的血清呈现出特异性反应，而兔血清需要进行预处理以消除其非特异性凝集素。经过这种预处理的人血清仍含有非特异性凝集素。在评估疫苗抗原性方面，乳胶凝集试验与补体结合试验及代谢抑制试验相比具有优势。

相似文献

1

Antibody response of animals to Mycoplasma pneumoniae measured by latex agglutination.通过乳胶凝集法测定动物对肺炎支原体的抗体反应。

Appl Microbiol. 1969 Feb;17(2):275-9. doi: 10.1128/am.17.2.275-279.1969.

2

Antimetabolic antibodies to Mycoplasma pneumoniae measured by tetrazolium reduction inhibition.

Proc Soc Exp Biol Med. 1966 Jul;122(3):786-90. doi: 10.3181/00379727-122-31252.

3

Direct haemagglutination by Mycoplasma pneumoniae and its inhibition by immune serum.肺炎支原体的直接血凝反应及其免疫血清对该反应的抑制作用。

J Med Microbiol. 1969 May;2(2):131-5. doi: 10.1099/00222615-2-2-131.

4

Antibodies to Mycoplasma pneumoniae: correlation of complement fixation and tetrazolium reduction inhibition tests.肺炎支原体抗体：补体结合试验与四氮唑还原抑制试验的相关性

Proc Soc Exp Biol Med. 1972 Sep;140(4):1294-7. doi: 10.3181/00379727-140-36661.

5

Heat lability of rabbit anti-Mycoplasma pneumoniae serum.兔抗肺炎支原体血清的热稳定性

Antonie Van Leeuwenhoek. 1972;38(2):193-200. doi: 10.1007/BF02328091.

6

[The specificity of antihepatic antibodies].[抗肝抗体的特异性]

Z Gesamte Exp Med Einschl Exp Chir. 1968;145(3):289-301.

7

Antibody response of swine experimentally infected with Mycoplasma hyosynoviae.经实验感染猪鼻支原体的猪的抗体反应。

Vet Microbiol. 1982 May;7(2):135-46. doi: 10.1016/0378-1135(82)90025-6.

8

Mycoplasma-latex agglutination reaction.支原体乳胶凝集反应。

J Bacteriol. 1966 Oct;92(4):1196-205. doi: 10.1128/jb.92.4.1196-1205.1966.

9

Serological cross-reaction between lipids of Mycoplasma pneumoniae and Mycoplasma neurolyticum.肺炎支原体与溶神经支原体脂质之间的血清学交叉反应。

Infect Immun. 1971 Aug;4(2):149-53. doi: 10.1128/iai.4.2.149-153.1971.

10

A simple preparation of antigen from Mycoplasma pneumoniae.一种从肺炎支原体中制备抗原的简单方法。

J Hyg Epidemiol Microbiol Immunol. 1971;15(1):73-81.

本文引用的文献

1

Application of a microtechnique to viral serological investigations.一种微技术在病毒血清学研究中的应用。

J Immunol. 1962 Mar;88:320-9.

2

Growth on artificial medium of an agent associated with atypical pneumonia and its identification as a PPLO.一种与非典型肺炎相关的病原体在人工培养基上的生长及其被鉴定为类胸膜肺炎微生物。

Proc Natl Acad Sci U S A. 1962 Jan 15;48(1):41-9. doi: 10.1073/pnas.48.1.41.

3

Latex agglutination by the reaction of human growth hormone with its antiserum.

Proc Soc Exp Biol Med. 1961 Jan;106:168-70. doi: 10.3181/00379727-106-26273.

4

A histoplasmin-latex agglutination test. I. Results with animal sera.

J Lab Clin Med. 1958 May;51(5):793-801.

5

Use of latex particles in serology of tuberculosis.

Am Rev Respir Dis. 1967 Apr;95(4):638-42. doi: 10.1164/arrd.1967.95.4.638.

6

Mycoplasma-latex agglutination reaction.支原体乳胶凝集反应。

J Bacteriol. 1966 Oct;92(4):1196-205. doi: 10.1128/jb.92.4.1196-1205.1966.

7

Antimetabolic antibodies to Mycoplasma pneumoniae measured by tetrazolium reduction inhibition.

Proc Soc Exp Biol Med. 1966 Jul;122(3):786-90. doi: 10.3181/00379727-122-31252.

8

The effect of kaolin on immunoglobulins: an improved technique to remove the nonspecific serum inhibitor of reovirus hemagglutination.高岭土对免疫球蛋白的影响：一种去除呼肠孤病毒血凝反应非特异性血清抑制剂的改良技术。

J Immunol. 1967 Jun;98(6):1136-42.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。