Gowland E, Kay H E, Spillman J C, Williamson J R
J Clin Pathol. 1969 Jul;22(4):460-4. doi: 10.1136/jcp.22.4.460.
The platelets of a patient with reticulum-cell sarcoma were found to exhibit agglutination and cytopathic changes when her blood was treated with EDTA but not with other anticoagulants. Investigation showed that the phenomenon was caused by a serum factor that was probably an antibody.
当用乙二胺四乙酸(EDTA)处理一名网状细胞肉瘤患者的血液时,发现其血小板出现凝集和细胞病变改变,而用其他抗凝剂处理时则未出现这种情况。研究表明,该现象是由一种可能为抗体的血清因子引起的。