Tschen J A, McGavran M H
Cancer. 1979 Oct;44(4):1388-92. doi: 10.1002/1097-0142(197910)44:4<1388::aid-cncr2820440432>3.0.co;2-o.
Sebaceous lymphadenoma is a rare, benign neoplasm of the parotid gland. In the 18 years since the initial report seven additional cases have been published. None includes ultrastructural studies or lipid analysis. Electron microscopy shows that the epithelial cells undergo a progressive maturation from basal to the typical lipid-laden mature sebaceous cells as in the cutaneous sebaceous glands. No morphologic differences are found between cutaneous sebaceous glands and the sebaceous glands in this parotid neoplasm. Thin-layer chromatography demonstrates the same type of lipids in the subaceous lymphadenoma as well as in cutaneous sebaceous glands. These findings suggest that the parotid salivary gland may be ectodermally rather than endodermally derived.
皮脂腺淋巴腺瘤是一种罕见的腮腺良性肿瘤。自首次报告以来的18年里，又发表了另外7例病例。均未包括超微结构研究或脂质分析。电子显微镜显示，上皮细胞经历从基底细胞到典型的充满脂质的成熟皮脂腺细胞的渐进性成熟，如同皮肤皮脂腺一样。在皮肤皮脂腺和这种腮腺肿瘤中的皮脂腺之间未发现形态学差异。薄层色谱法显示皮脂腺淋巴腺瘤和皮肤皮脂腺中脂质类型相同。这些发现提示腮腺唾液腺可能来源于外胚层而非内胚层。
