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Junctional intercellular communication pattern of cultured human breast cancer cells.

作者信息

Fentiman I S, Hurst J, Ceriani R L, Taylor-Papadimitriou J

出版信息

Cancer Res. 1979 Nov;39(11):4739-43.

PMID:498101
Abstract

Junctional intercellular communication between several established human breast cancer cell lines and a variety of mammalian cells has been examined. All the cancer cell lines were found to be either noncommunicators or nonselective communicators. This contrasts with normal human mammary epithelium which shows selectivity in junctional communication. Loss of selectivity in junctional communication appears to be a general feature of cultured human breast cancer cells.

摘要

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引用本文的文献

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Connexins 26, 32 and 43 are expressed in virgin, pregnant and lactating mammary glands.连接蛋白26、32和43在未孕、妊娠和哺乳期乳腺中均有表达。
Dev Growth Differ. 1995 Aug;37(4):421-431. doi: 10.1046/j.1440-169X.1995.t01-3-00009.x.
2
Measurement of gap junctional communication by fluorescence activated cell sorting.
In Vitro Cell Dev Biol Anim. 1994 Nov;30A(11):796-802. doi: 10.1007/BF02631304.
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Potential role of the src gene product in inhibition of gap-junctional communication in NIH/3T3 cells.src基因产物在抑制NIH/3T3细胞间隙连接通讯中的潜在作用。
Proc Natl Acad Sci U S A. 1985 Aug;82(16):5360-4. doi: 10.1073/pnas.82.16.5360.
4
Lipids in gap junction assembly and function.缝隙连接组装与功能中的脂质。
Lipids. 1990 Aug;25(8):419-27. doi: 10.1007/BF02538083.
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Aberrant expression and function of gap junctions during carcinogenesis.缝隙连接在致癌过程中的异常表达与功能
Environ Health Perspect. 1991 Jun;93:191-7. doi: 10.1289/ehp.9193191.
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Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines.间隙连接蛋白的转录下调会阻断人乳腺肿瘤细胞系中的细胞间连接通讯。
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