金黄色葡萄球菌溶菌酶对人成纤维细胞的影响。
Effects of Staphylococcus aureus lysozyme on human fibroblasts.
作者信息
Satta G, Varaldo P E, Azzarone B, Romanzi C A
出版信息
Cell Biol Int Rep. 1979 Sep;3(6):525-33. doi: 10.1016/0309-1651(79)90088-2.
PMID:498287
Abstract
The purified lysozyme excreted by Staphylococcus aureus strains promotes elongation and spreading on plastic surfaces and stimulates DNA synthesis of human fibroblasts (WI38). This enzyme also raises twofold the saturation density level of cultures of these cells. It is suggested that the primitive and main effect of lysozyme on fibroblasts is the triggering of morphogenesis.
摘要
金黄色葡萄球菌菌株分泌的纯化溶菌酶可促进其在塑料表面的伸长和扩散，并刺激人成纤维细胞（WI38）的DNA合成。这种酶还能使这些细胞培养物的饱和密度水平提高两倍。有人认为，溶菌酶对成纤维细胞的原始和主要作用是触发形态发生。
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