Reversibility of the toxicity of methotrexate by dihydrofolate in mice.
作者信息
Tzortzatou F
出版信息
Clin Exp Pharmacol Physiol. 1979 Sep-Oct;6(5):581-3. doi: 10.1111/j.1440-1681.1979.tb00041.x.
Abstract
- Dihydrofolate in mice can reverse the toxicity of a lethal dose of methotrexate. 2. The 'rescue' of mice after a lethal dose of methotrexate suggests that dihydrofolate could have a clinical use as an antidote in treating methotrexate-induced toxicity.
摘要
Zotero 插件