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Plasma levels of chlorimipramine and its demethyl metabolite during treatment of depression.

作者信息

Träskman L, Asberg M, Bertilsson L, Cronholm B, Mellström B, Neckers L M, Sjöqvist F, Thorén P, Tybring G

出版信息

Clin Pharmacol Ther. 1979 Nov;26(5):600-10. doi: 10.1002/cpt1979265600.

DOI:10.1002/cpt1979265600
PMID:498703
Abstract
摘要

相似文献

1
Plasma levels of chlorimipramine and its demethyl metabolite during treatment of depression.抑郁症治疗期间氯米帕明及其去甲基代谢物的血浆水平。
Clin Pharmacol Ther. 1979 Nov;26(5):600-10. doi: 10.1002/cpt1979265600.
2
Monoamine metabolites in cerebrospinal fluid and serotonin uptake inhibition during treatment with chlorimipramine.氯米帕明治疗期间脑脊液中的单胺代谢物及5-羟色胺摄取抑制作用。
Clin Pharmacol Ther. 1977 Feb;21(2):201-7. doi: 10.1002/cpt1977212201.
3
Plasma concentrations of clomipramine and its N-desmethyl metabolite in depressive patients following treatment with various dosage regimes of clomipramine.抑郁症患者在接受不同剂量氯米帕明治疗后血浆中氯米帕明及其N-去甲基代谢物的浓度。
Postgrad Med J. 1977;53 Suppl 4:63-76.
4
Plasma concentration of clomipramine and desmethylclomipramine and clinical response in depressed patients.
Postgrad Med J. 1980;56 Suppl 1:130-3.
5
Clomipramine plasma level and clinical response.氯米帕明血药浓度与临床反应。
Postgrad Med J. 1977;53 Suppl 4:139-45.
6
Differential effect of chlorimipramine and nortriptyline on cerebrospinal fluid metabolites of serotonin and noradrenaline in depression.氯米帕明和去甲替林对抑郁症患者脑脊液中5-羟色胺和去甲肾上腺素代谢物的不同作用
Eur J Clin Pharmacol. 1974 Aug 23;7(5):365-8. doi: 10.1007/BF00558208.
7
Plasma levels and clinical improvement--a comparative study of clomipramine and amitriptyline in depression.
Postgrad Med J. 1980;56 Suppl 1:127-9.
8
[N-dealkylation of chlorimipramine and chlorpromazine in patients undergoing chronic treatment with both drugs: preliminary results].
Boll Soc Ital Biol Sper. 1984 Sep 30;60(9):1727-33.
9
Chronic chlorimipramine does not reverse the reduction of cerebrospinal fluid Met-enkephalin-like immunoreactivity in chronic-pain patients.慢性氯米帕明不能逆转慢性疼痛患者脑脊液中脑啡肽样免疫反应性的降低。
Clin Neuropharmacol. 1987 Oct;10(5):434-42. doi: 10.1097/00002826-198710000-00005.
10
Plasma level studies with clomipramine (anafranil).
J Int Med Res. 1977;5(1 Suppl):98-107.

引用本文的文献

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The Role of Metabolites of Antidepressants in the Treatment of Depression.抗抑郁药代谢物在抑郁症治疗中的作用。
CNS Drugs. 1997 Apr;7(4):273-312. doi: 10.2165/00023210-199707040-00003.
2
The impact of the CYP2D6-polymorphism on dose recommendations for current antidepressants.细胞色素P450 2D6（CYP2D6）基因多态性对当前抗抑郁药剂量推荐的影响。
Eur Arch Psychiatry Clin Neurosci. 2006 Aug;256(5):287-93. doi: 10.1007/s00406-006-0663-5.
3
Effect of clomipramine on monoamine metabolites in the cerebrospinal fluid of behaviorally normal dogs.
氯米帕明对行为正常犬脑脊液中单胺代谢物的影响。
Can J Vet Res. 2000 Apr;64(2):123-9.
4
Metabolism of tricyclic antidepressants.三环类抗抑郁药的代谢
Cell Mol Neurobiol. 1999 Jun;19(3):373-409. doi: 10.1023/a:1006949816036.
5
Obsessive-compulsive disorder in elderly patients.老年患者的强迫症
Drugs Aging. 1995 Dec;7(6):438-48. doi: 10.2165/00002512-199507060-00004.
6
Pharmacokinetic optimisation of tricyclic antidepressant therapy.三环类抗抑郁药治疗的药代动力学优化
Clin Pharmacokinet. 1993 Apr;24(4):301-18. doi: 10.2165/00003088-199324040-00004.
7
Relationship between the plasma concentration of clomipramine and desmethylclomipramine in depressive patients and the clinical response.抑郁症患者中氯米帕明和去甲氯米帕明的血浆浓度与临床反应之间的关系。
Eur J Clin Pharmacol. 1982;22(1):15-20. doi: 10.1007/BF00606419.
8
Pharmacokinetic interactions with antiepileptic drugs.与抗癫痫药物的药代动力学相互作用。
Clin Pharmacokinet. 1982 Jan-Feb;7(1):57-84. doi: 10.2165/00003088-198207010-00004.
9
Amitriptyline and nortriptyline response profiles in unipolar depressed patients.单相抑郁症患者中阿米替林和去甲替林的反应情况
Psychopharmacology (Berl). 1982;77(2):193-7. doi: 10.1007/BF00431947.
10
Effects of zimelidine and desipramine on serotonin and noradrenaline uptake mechanisms in relation to plasma concentrations and to therapeutic effects during treatment of depression.齐美利定和地昔帕明对5-羟色胺和去甲肾上腺素摄取机制的影响与抑郁症治疗期间的血浆浓度及治疗效果的关系。
Psychopharmacology (Berl). 1981;74(4):297-305. doi: 10.1007/BF00432735.