沙眼-包涵体结膜炎病原体在狒狒体内传代后的毒力。
Virulence of trachoma-inclusion conjunctivitis agent after passage in baboons.
作者信息
Moore J E, Griffiths M S, Pearce J H
出版信息
Br J Exp Pathol. 1970 Jun;51(3):298-304.
Abstract
The virulence of a strain of trachoma-inclusion conjunctivitis agent was increased by passage in baboons as judged by the severity of clinical signs and the number of inclusions found in conjunctival scrapings. Clinical scores increased substantially with a corresponding rise of from 5-20 to several hundred inclusions per conjunctival smear. Organisms from the heavily infected animals were reduced in infectivity for the baboon after 2 passages in chick embryos.
摘要
根据临床症状的严重程度以及结膜刮片中发现的包涵体数量判断，一株沙眼-包涵体结膜炎病原体在狒狒体内传代后毒力增强。临床评分大幅增加，同时结膜涂片上的包涵体数量相应地从每片5 - 20个增加到数百个。在鸡胚中传代2次后，来自重度感染动物的病原体对狒狒的感染性降低。
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