Breisach G, Stünzner D, Withalm H, Kurz R, Höllwarth M
Dtsch Med Wochenschr. 1979 Oct 5;104(40):1409-12. doi: 10.1055/s-0028-1129111.
Tetanus antibody determinations in 109 children aged 1 1/2 to 15 1/2 years showed that 98.2% had a sufficiently protective tetanus antitoxin titre. There were no significant differences between completely and incompletely first immunised children. Increased titres of up to 25 IU/ml serum were found shortly after multiple boostering. According to the observed titres boostering after trauma is at the earliest necessary after 5 years in complete or incomplete primary immunisation or after the last boostering. Passive immunisation is only indicated in the traumatised non-immunised and in patients with wounds of larger standing who have not been immunised for more than 5 years.
对109名年龄在1岁半至15岁半的儿童进行破伤风抗体检测,结果显示98.2%的儿童破伤风抗毒素滴度具有足够的保护性。初次免疫完全和不完全的儿童之间无显著差异。多次加强免疫后不久,血清滴度最高可增加至25 IU/ml。根据观察到的滴度,在完全或不完全的初次免疫后或最后一次加强免疫后5年,创伤后最早有必要进行加强免疫。被动免疫仅适用于受伤的未免疫者以及伤口长期存在且未免疫超过5年的患者。