Hok K A, Nieman R, Lackey J O, Cabasso V J
Appl Microbiol. 1970 Jul;20(1):6-10. doi: 10.1128/am.20.1.6-10.1970.
A study of the presence of Australia antigen (Au/SH) was conducted over a period of 21 weeks among volunteer plasma donors living in a prison and being monitored for serum glutamic oxalacetic transaminase (SGOT). A good correlation was observed between the level of SGOT and presence of Au/SH, the latter being present in 33% of donors with SGOT values higher than 101 Karmen units and in 12% of those with SGOT values of 41 to 100 units. Furthermore, none of the 87 donors with all SGOT values below 40 was found positive for Au/SH. It should be noted, however, that single specimens only were tested from 72 of the 87 individuals. Au/SH was detected with equivalent efficiency by both agar gel precipitation and complement fixation procedures. Implications of these findings in the prognostication of hepatitis carrier state are discussed.
对一所监狱中志愿血浆捐献者进行了为期21周的澳大利亚抗原（Au/SH）检测，这些捐献者同时接受血清谷氨酸草酰乙酸转氨酶（SGOT）监测。观察到SGOT水平与Au/SH的存在之间存在良好的相关性，在SGOT值高于101卡门单位的捐献者中，33%存在Au/SH，而在SGOT值为41至100单位的捐献者中，12%存在Au/SH。此外，87名SGOT值均低于40的捐献者中，没有一人Au/SH检测呈阳性。然而，应当指出的是，87名个体中只有72人的单个样本进行了检测。通过琼脂凝胶沉淀法和补体结合法检测Au/SH的效率相当。文中讨论了这些发现对肝炎携带者状态预后的影响。
