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伦敦肝炎患者体内的澳大利亚- SH抗原。

Australia-SH antigen in hepatitis patients in London.

作者信息

Cossart Y, Taylor P E, Vahrman J, Zuckerman A J

出版信息

Br Med J. 1969 Sep 27;3(5673):755-6. doi: 10.1136/bmj.3.5673.755.

Abstract

Australia-SH antigen was found in 11 out of 27 sera (40%) obtained from patients with acute viral hepatitis soon after their admission to hospital. Six out of 11 positive sera were collected within the first 12 days of illness; die remaining five were collected between the 13th and 30th days. The antigen was detected by immunodiffusion in agarose gel, five different indicator sera containing Australia-SH antibodies being used. The specificity of these sera was found to be very similar.All of the patients' sera were examined independently by two separate laboratories. The results obtained by the laboratories were in close agreement, though the techniques varied in detail.

摘要

在27例急性病毒性肝炎患者入院后不久采集的血清中,有11例(40%)检测到澳大利亚SH抗原。11份阳性血清中有6份是在发病后的前12天内采集的;其余5份是在第13天至第30天之间采集的。采用免疫扩散法在琼脂糖凝胶中检测该抗原,使用了5种不同的含有澳大利亚SH抗体的指示血清。发现这些血清的特异性非常相似。所有患者的血清均由两个独立的实验室分别进行检测。尽管检测技术在细节上有所不同,但两个实验室获得的结果非常一致。

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