Kozarov I, Popdimitrov I
Eksp Med Morfol. 1979;18(3):183-5.
The authors caused buring of III to IV degree, 10--15% in rats of the Wistar strain. The animals were divided into 4 groups: 1) healthy; 2) burned-nontreated; 3) burned-treated with saline; and 4) burned-treated with hydrolysate. Saline and hydrolysate were administered immediately after thermic trauma, and vascularization was examined by means of radioisotopic methods (86Rb) six hours after burning. Increased blood flow in the internal organs was found 6 hours after inducing the thermic trauma, excluding the pancreas. Saline revealed a certain tendency to normalization of the circulation, but this effect was insignificant and could not be referred to all organs. The protein hydrolysate most sensitively and significantly corrected deviations as in almost all organs they reached practically the norm.
作者在Wistar品系大鼠身上造成了10%-15%的Ⅲ至Ⅳ度烧伤。将动物分为4组：1）健康组；2）烧伤未治疗组；3）烧伤后用生理盐水治疗组；4）烧伤后用水解物治疗组。热创伤后立即给予生理盐水和水解物，并在烧伤6小时后用放射性同位素方法（86Rb）检查血管生成情况。热创伤诱导6小时后，除胰腺外，发现内脏器官血流量增加。生理盐水显示出循环趋于正常的某种趋势，但这种作用不显著，且并非对所有器官都有作用。蛋白质水解物最敏感且显著地纠正了偏差，因为几乎在所有器官中它们实际上都达到了正常水平。
