Ferrant A, Cauwe F
Eur J Nucl Med. 1979 Jun 1;4(3):223-9. doi: 10.1007/BF00620490.
A study was carried out to investigate the use of a gamma camera for quantitative measurement of the absolute radioactivity in internal organs. Phantoms simulating different patient conditions were used to derive the attenuation correction factor and the conversion factor which relates a known radioactive dose to organ activity. The delimitation of the source image was established by means of an isocontour of maximum count rate. A mathematical approach was used for achievement of isosensitivity with depth of the organ and for correction for background. The accuracy of the procedure was proven by the recovery over the stomach area of the ingested activity. The method is applied to the quantitative assessment of the splenic red-cell volume.
开展了一项研究，以调查使用伽马相机对内部器官中的绝对放射性进行定量测量。使用模拟不同患者状况的体模来推导衰减校正因子和将已知放射性剂量与器官活性相关联的转换因子。通过最大计数率的等轮廓线来确定源图像的边界。采用数学方法来实现器官深度方向上的等灵敏度以及背景校正。通过摄取活性在胃部区域的回收率证明了该程序的准确性。该方法应用于脾脏红细胞体积的定量评估。
