Richter R F, Ambrosius H
Eur J Immunol. 1979 Jul;9(7):578-80. doi: 10.1002/eji.1830090716.
Carp synthesize highly specific anti-idiotypic antibodies of the IgM class. Ant-idiotypic antibodies could be elicited in these animals by a human IgM myeloma protein and were detected in a passive hemagglutination assay. The agglutination was completely inhibited by approximately 0.15 microgram homologous antigen, whereas a 100 000-fold excess of a heterologous IgM myeloma protein of the same L chain type did not produce any inhibition. A possible subgroup specificity of carp anti-idiotypic antisera can be excluded.
鲤鱼能合成IgM类高度特异性的抗独特型抗体。人IgM骨髓瘤蛋白可在这些动物体内引发抗独特型抗体，并通过被动血凝试验检测到。约0.15微克同源抗原可完全抑制凝集反应，而相同L链类型的异源IgM骨髓瘤蛋白过量10万倍也不会产生任何抑制作用。鲤鱼抗独特型抗血清不存在可能的亚组特异性。
