Richter R F, von Broen I M, Ambrosius H
Allerg Immunol (Leipz). 1984;30(4):237-41.
Previous investigations about the specificity of carp anti-idiotypic sera could be confirmed by comparison with corresponding antisera of guinea pigs. 3 carp antihuman myeloma-protein sera rendered as idiotypic specific after an appropriate absorption were tested in the passive hemagglutination inhibition test. They showed no difference to the parallel tested guinea pig antisera. It can be assumed that between fish antibodies and antibodies of mammals no functional difference exists in respect of antigen binding. On the other hand mammals exhibit a higher extent of structural antibody heterogeneity.
以往关于鲤鱼抗独特型血清特异性的研究，通过与豚鼠相应抗血清对比得以证实。3种经适当吸收后呈现独特型特异性的鲤鱼抗人骨髓瘤蛋白血清，在被动血凝抑制试验中进行了检测。它们与平行检测的豚鼠抗血清并无差异。可以假定，在抗原结合方面，鱼类抗体与哺乳动物抗体之间不存在功能差异。另一方面，哺乳动物抗体在结构上表现出更高程度的异质性。
