Hounsgaard J, Yamamoto C
Exp Brain Res. 1979 Oct;37(2):387-98. doi: 10.1007/BF00237721.
Extracellular spikes were recorded simultaneously from dendrites and somata of Purkinje cells in thin cerebellar sections. Spontaneously occurring dendritic spikes were biphasic with the initial phase positive. Triphasic dendritic spikes with a large negative phase appeared during electrophoretic application of glutamate. In media containing procaine, tetrodotoxin, or high concentrations of KCl, negative dendritic spikes occurred whereas soma spikes were abolished. The negative dendritic spikes were suppressed by CoCl2 or MnCl2. Electrical stimulation elicited climbing fibre responses in somata and large negative waves in dendrites. Spikes of dendritic origin were different from those reflecting electrotonic spread of soma spikes. The relation between soma spikes and active dendritic spikes is discussed.
在薄小脑切片中，同时从浦肯野细胞的树突和胞体记录细胞外尖峰。自发出现的树突尖峰是双相的，初始相为正。在电泳施加谷氨酸期间，出现具有大负相的三相树突尖峰。在含有普鲁卡因、河豚毒素或高浓度氯化钾的培养基中，出现负性树突尖峰，而胞体尖峰被消除。负性树突尖峰被氯化钴或氯化锰抑制。电刺激在胞体中引发攀缘纤维反应，在树突中引发大的负波。源于树突的尖峰与反映胞体尖峰电紧张扩布的尖峰不同。讨论了胞体尖峰与活跃树突尖峰之间的关系。
