Sunthonpalin P, Arkins J A, Fink J N
Clin Exp Immunol. 1971 May;8(5):825-34.
Homocytotropic antibody induced with ragweed and timothy pollen extract has been produced in non-atopic dogs. Characterization of the antibody was carried out by direct skin tests, passive transfer, tanned red cell haemagglutination, Sephadex filtration and immunoelectrophoresis. Two types of antibody were induced. A 7S antibody which had skin sensitizing characteristics and a 19S antibody which was the haemagglutinating antibody and 2ME sensitive. The findings are similar to that seen in spontaneous canine atopy except that the dogs did not respond with respiratory or systemic symptoms after antigenic challenge.
已在非特应性犬中产生了由豚草和梯牧草花粉提取物诱导的亲同种细胞抗体。通过直接皮肤试验、被动转移、鞣酸红细胞血凝反应、葡聚糖凝胶过滤和免疫电泳对该抗体进行了特性鉴定。诱导出了两种类型的抗体。一种是具有皮肤致敏特性的7S抗体，另一种是血凝抗体且对2-巯基乙醇敏感的19S抗体。这些发现与自发性犬特应性皮炎中所见相似，只是这些犬在抗原攻击后未出现呼吸道或全身症状。
